Date published: 2025-9-18

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ADH Inhibitors

ADH inhibitors constitute a chemical class of compounds that and reversibly target ADH (alcohol dehydrogenase), an enzyme involved in the metabolism of alcohol (ethanol) and other alcohols in the body. ADH catalyzes the conversion of alcohols to their corresponding aldehydes or ketones, contributing to the breakdown of ethanol into acetaldehyde and further metabolites. The inhibition of ADH activity is a subject of significant interest in scientific research, aimed at understanding its pivotal role in alcohol metabolism and its potential implications in various physiological and pathological processes. These inhibitors are carefully engineered to interact with specific regions or binding sites on the ADH enzyme, thereby disrupting its enzymatic activity and altering the kinetics of alcohol metabolism. Researchers employ ADH inhibitors in biochemical and cellular studies to investigate the intricate mechanisms of alcohol metabolism and its potential effects on alcohol-related disorders and other aspects of human health. The design and development of these inhibitors are based on a comprehensive understanding of ADH's structural features and its involvement in the metabolism of diverse alcohols, providing valuable tools for advancing research in the fields of enzymology and alcohol-related research.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Disulfiram

97-77-8sc-205654
sc-205654A
50 g
100 g
$52.00
$87.00
7
(1)

Disulfiram (CAS 97-77-8) is a chemical compound known to act as an ADH inhibitor. It interferes with the function of alcohol dehydrogenase, an enzyme responsible for metabolizing alcohol in the body. By inhibiting ADH, Disulfiram affects the breakdown of ethanol, leading to the accumulation of acetaldehyde, which can cause unpleasant reactions when alcohol is consumed.

Disulfiram-d20

1216403-88-1sc-218249
sc-218249A
1 mg
10 mg
$398.00
$2856.00
(0)

Disulfiram-d20 (CAS 1216403-88-1) is a deuterated form of Disulfiram, acting as an inhibitor of ADH (alcohol dehydrogenase). By inhibiting ADH, it interferes with the metabolism of alcohol (ethanol) in the body, leading to the accumulation of acetaldehyde upon alcohol consumption.

Penicillic acid

90-65-3sc-205796
sc-205796A
5 mg
25 mg
$127.00
$275.00
5
(0)

Penicillic acid (CAS 90-65-3) is known to act as an inhibitor of ADH (alcohol dehydrogenase). It interferes with the enzymatic activity of ADH, the key enzyme responsible for metabolizing alcohol (ethanol) in the body. By inhibiting ADH, penicillic acid affects the breakdown of ethanol, leading to altered alcohol metabolism and potential physiological effects.

Fomepizole

7554-65-6sc-252838
1 g
$74.00
1
(1)

Fomepizole (CAS 7554-65-6) is a chemical compound known for its role as an ADH (alcohol dehydrogenase) inhibitor. It selectively targets and inhibits the activity of ADH, the enzyme responsible for the metabolism of alcohol (ethanol) and other alcohols in the body. By inhibiting ADH, fomepizole interferes with the breakdown of ethanol, leading to altered alcohol metabolism and potential physiological effects.

4-Bromopyrazole

2075-45-8sc-254636
1 g
$54.00
(0)

4-Bromopyrazole (CAS 2075-45-8) acts as an inhibitor of ADH (alcohol dehydrogenase), a key enzyme involved in the metabolism of alcohol (ethanol) and other alcohols in the body. By inhibiting ADH, 4-Bromopyrazole interferes with the breakdown of ethanol, leading to altered alcohol metabolism and potential physiological effects.

3-Hydroxypropionamide

2651-43-6sc-209620
100 mg
$372.00
(0)

3-Hydroxypropionamide (CAS 2651-43-6) functions as an inhibitor of ADH (alcohol dehydrogenase), an enzyme responsible for metabolizing alcohol (ethanol) and other alcohols in the body. By inhibiting ADH, 3-Hydroxypropionamide interferes with the enzymatic breakdown of ethanol, potentially leading to altered alcohol metabolism and physiological effects.

4-Methylpyrazole hydrochloride

56010-88-9sc-214254
sc-214254A
100 mg
500 mg
$141.00
$455.00
1
(1)

4-Methylpyrazole hydrochloride (CAS 56010-88-9) acts as an inhibitor of ADH (alcohol dehydrogenase), an enzyme responsible for metabolizing alcohol (ethanol) and other alcohols in the body. By inhibiting ADH, 4-Methylpyrazole hydrochloride interferes with the enzymatic breakdown of ethanol, potentially leading to altered alcohol metabolism and physiological effects.

Cyanamide

420-04-2sc-239592
sc-239592A
5 g
25 g
$21.00
$77.00
(0)

Cyanamide is a compound that inhibits ADH and has been studied for its potential role in alcohol aversion therapy.

1,10-Phenanthroline-d8

90412-47-8sc-255889
500 mg
$1250.00
(0)

1,10-phenanthroline is a metal chelator that can inhibit ADH activity.

Pyrazole

288-13-1sc-255450
sc-255450A
5 g
25 g
$19.00
$51.00
(0)

Certain pyrazole compounds have been reported to inhibit ADH.