ACTBL2 Inhibitors constitute a specialized class of chemical compounds designed to selectively hinder the activity of ACTBL2, also known as Actin, Beta-Like 2. ACTBL2 is a member of the actin protein family, which plays a fundamental role in cellular structure, motility, and intracellular transport. The development of inhibitors targeting ACTBL2 serves as a crucial tool for scientific exploration, offering researchers specific agents to dissect the molecular functions and regulatory roles associated with this particular actin isoform. As part of the broader actin family, ACTBL2 likely contributes to the dynamic organization of the cytoskeleton, influencing cellular shape, migration, and the maintenance of cellular integrity.
The synthesis and optimization of ACTBL2 inhibitors require a detailed understanding of the structural characteristics of the actin isoform and its interactions within cellular pathways. These inhibitors are meticulously designed for specificity, aiming to selectively bind to key regions of ACTBL2 and interfere with its normal cellular functions. By utilizing ACTBL2 inhibitors in experimental settings, researchers can explore the consequences of isoform-specific inhibition on cellular processes, shedding light on the specific molecular pathways influenced by ACTBL2. The study of ACTBL2 inhibitors contributes to the broader exploration of cytoskeletal dynamics, providing insights into the intricate molecular machinery that underlies fundamental cellular functions related to cell shape, movement, and structural integrity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ellipticine | 519-23-3 | sc-200878 sc-200878A | 10 mg 50 mg | $145.00 $569.00 | 4 | |
Ellipticine intercalates into DNA, disrupting DNA structure and inhibiting transcription, leading to decreased ACTBL2 mRNA. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $52.00 $125.00 $182.00 | 11 | |
Homoharringtonine inhibits protein synthesis by binding to the ribosome, resulting in reduced ACTBL2 expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin C1 binds to DNA and inhibits transcription, causing a reduction in the expression of ACTBL2. | ||||||
Thiostrepton | 1393-48-2 | sc-203412 sc-203412A | 1 g 5 g | $117.00 $423.00 | 10 | |
Thiostrepton inhibits protein synthesis by binding to the ribosome, potentially reducing the production of ACTBL2. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
Camptothecin inhibits DNA topoisomerase I, inducing DNA damage and inhibiting transcription, leading to decreased ACTBL2 mRNA. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $66.00 $101.00 $143.00 | 85 | |
Mitomycin C cross-links DNA, inhibiting transcription and potentially reducing the synthesis of ACTBL2 mRNA. | ||||||
Emetine | 483-18-1 | sc-470668 sc-470668A sc-470668B sc-470668C | 1 mg 10 mg 50 mg 100 mg | $440.00 $900.00 $1400.00 $2502.00 | ||
Emetine inhibits protein synthesis by binding to the ribosome, leading to a decrease in ACTBL2 expression. | ||||||
Blasticidin S Hydrochloride | 3513-03-9 | sc-204655A sc-204655 | 25 mg 100 mg | $367.00 $520.00 | 20 | |
Blasticidin S induces premature termination during translation, inhibiting protein synthesis and reducing ACTBL2 levels. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide inhibits RNA polymerase, disrupting transcription and potentially decreasing the expression of ACTBL2. | ||||||