Date published: 2026-7-23

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 191 to 200 of 372 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Ethyl fumaroyl chloride

26367-48-6sc-235048
1 g
$99.00
(0)

Ethyl fumaroyl chloride is a distinctive acid halide featuring a conjugated double bond system that enhances its reactivity through resonance stabilization. This compound exhibits a high degree of electrophilicity, making it particularly effective in acylation reactions with nucleophiles. Its unique geometric configuration allows for selective interactions with various functional groups, promoting regioselectivity in synthetic pathways. Additionally, the presence of the fumaroyl group contributes to its ability to participate in cycloaddition reactions, expanding its utility in organic synthesis.

(2,2-dichlorocyclopropyl)methanesulfonyl chloride

sc-343267
sc-343267A
250 mg
1 g
$197.00
$399.00
(0)

(2,2-Dichlorocyclopropyl)methanesulfonyl chloride is a notable acid halide characterized by its strained cyclopropyl ring, which imparts unique reactivity patterns. The presence of two chlorine atoms enhances its electrophilic nature, facilitating rapid nucleophilic substitution reactions. This compound's ability to form stable sulfonyl derivatives allows for diverse synthetic applications. Its distinct steric and electronic properties promote selective interactions, influencing reaction kinetics and pathways in organic transformations.

2-Difluoromethoxy-benzenesulfonyl chloride

77798-10-8sc-357543
sc-357543A
250 mg
1 g
$450.00
$1150.00
(0)

2-Difluoromethoxy-benzenesulfonyl chloride is an intriguing acid halide distinguished by its electron-withdrawing difluoromethoxy group, which significantly enhances its electrophilicity. This feature promotes swift nucleophilic attack, leading to efficient formation of sulfonamide derivatives. The compound's unique molecular structure allows for selective reactivity, influencing the kinetics of substitution reactions and enabling tailored synthetic pathways in complex organic synthesis.

3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl Chloride

4462-55-9sc-209454
10 g
$200.00
(0)

3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride is a notable acid halide characterized by its highly reactive carbonyl group, which facilitates rapid acylation reactions. The presence of the dichlorophenyl moiety enhances its electrophilic nature, allowing for selective interactions with nucleophiles. This compound exhibits unique reactivity patterns, enabling the formation of diverse derivatives through controlled reaction conditions, thus influencing synthetic strategies in organic chemistry.

N-Ethyl-N-methylcarbamoyl Chloride

42252-34-6sc-212206
10 g
$280.00
(0)

N-Ethyl-N-methylcarbamoyl Chloride is a distinctive acid halide known for its ability to engage in nucleophilic acyl substitution reactions. The presence of both ethyl and methyl groups on the nitrogen atom enhances steric effects, influencing reaction kinetics and selectivity. This compound's reactivity is further amplified by its carbonyl functionality, allowing for efficient formation of amides and other derivatives, making it a versatile intermediate in synthetic pathways.

4-(Phenylazo)benzoyl chloride

104-24-5sc-223601
1 g
$88.00
(0)

4-(Phenylazo)benzoyl chloride is a notable acid halide characterized by its azo group, which introduces unique electronic properties that influence its reactivity. The presence of the phenylazo moiety enhances the electrophilicity of the carbonyl carbon, facilitating rapid nucleophilic attacks. This compound exhibits distinct pathways in acylation reactions, often leading to the formation of azo-containing derivatives. Its ability to stabilize intermediates through resonance contributes to its diverse reactivity in organic synthesis.

Behenoyl chloride

21132-76-3sc-214577
1 g
$150.00
(0)

Behenoyl chloride is a long-chain acid halide distinguished by its aliphatic structure, which imparts unique hydrophobic characteristics. This compound exhibits enhanced reactivity due to the steric effects of its extended carbon chain, influencing reaction kinetics in acylation processes. Its ability to form stable acyl intermediates allows for selective reactions with nucleophiles, leading to the synthesis of various esters and amides. The compound's distinct physical properties, such as solubility in organic solvents, further facilitate its role in diverse chemical transformations.

Stearoyl chloride

112-76-5sc-215905
100 ml
$79.00
(0)

Stearoyl chloride is a saturated fatty acid halide characterized by its long hydrocarbon chain, which enhances its lipophilicity and reactivity. This compound readily undergoes nucleophilic acyl substitution, making it a potent acylating agent. Its unique structure allows for specific interactions with various nucleophiles, promoting efficient esterification and amidation reactions. Additionally, the presence of the acyl chloride functional group contributes to its high reactivity, enabling rapid formation of acyl derivatives in diverse synthetic pathways.

Fmoc chloride

28920-43-6sc-215054
sc-215054A
1 g
5 g
$64.00
$196.00
(0)

Fmoc chloride is an aromatic acid halide distinguished by its bulky fluorenylmethoxycarbonyl group, which imparts steric hindrance and influences reaction selectivity. This compound exhibits a strong electrophilic character, facilitating nucleophilic attack by amines and alcohols. Its unique structure allows for the formation of stable intermediates, enhancing reaction kinetics in peptide synthesis. The presence of the chloride atom further increases its reactivity, enabling efficient acylation processes in various organic transformations.

Benzoyl chloride

98-88-4sc-214588
sc-214588A
500 ml
1 L
$32.00
$72.00
(0)

Benzoyl chloride is a reactive acid halide characterized by its aromatic benzoyl group, which enhances its electrophilic nature. This compound readily undergoes nucleophilic acyl substitution, making it a key player in acylation reactions. Its ability to form stable acyl intermediates accelerates reaction rates, while the presence of the chlorine atom promotes the formation of byproducts through elimination pathways. The compound's volatility and reactivity with water also highlight its behavior in hydrolysis reactions, leading to the generation of benzoic acid.