Molecular structure of Ethyl fumaroyl chloride, CAS Number: 26367-48-6
Ethyl fumaroyl chloride (CAS 26367-48-6)
Alternate Names:
(E)-3-(Chloroformyl)-acrylic acid ethyl ester; Ethyl fumaryl chloride
Application:
Ethyl fumaroyl chloride is an acid chloride compound for proteomics research
CAS Number:
26367-48-6
Purity:
≥97%
Molecular Weight:
162.57
Molecular Formula:
C6H7ClO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ethyl fumaroyl chloride functions as an acylating agent in organic synthesis. It is used to introduce the fumaryl group into various organic molecules, allowing for the modification of their chemical properties. The mechanism of action of ethyl fumaroyl chloride involves the reaction of the acyl chloride group with nucleophilic functional groups, such as amines or alcohols, leading to the formation of amides or esters, respectively. Ethyl Fumaroyl Chloride reaction occurs through nucleophilic acyl substitution, where the acyl chloride group is replaced by the nucleophile, resulting in the formation of a new covalent bond.
Ethyl fumaroyl chloride (CAS 26367-48-6) References
- Acylammonium salts as dienophiles in Diels-Alder/lactonization organocascades. | Abbasov, ME., et al. 2014. J Am Chem Soc. 136: 4492-5. PMID: 24588428
- Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells. | Kastrati, I., et al. 2017. J Vis Exp.. PMID: 28190074
- Enantioselective Diels-Alder-lactamization organocascades employing a furan-based diene. | Abbasov, ME., et al. 2017. Org Biomol Chem. 15: 3179-3183. PMID: 28358148
- Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application. | Abbasov, ME., et al. 2017. Chem Sci. 8: 1511-1524. PMID: 28616147
- HYCO-3, a dual CO-releaser/Nrf2 activator, reduces tissue inflammation in mice challenged with lipopolysaccharide. | Motterlini, R., et al. 2019. Redox Biol. 20: 334-348. PMID: 30391826
- Crystal structure and Hirshfeld surface analysis of ethyl (4R,4aS)-2-methyl-5,8-dioxo-6-phenyl-4a,5,6,7,7a,8-hexa-hydro-4H-furo[2,3-f]iso-indole-4-carboxyl-ate. | Zaytsev, VP., et al. 2021. Acta Crystallogr E Crystallogr Commun. 77: 86-90. PMID: 33614131
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ethyl fumaroyl chloride, 1 g | sc-235048 | 1 g | $99.00 |