AARS2 Activators
AARS2 activators encompass a range of chemicals that may indirectly modulate the protein AARS2 by focusing on mitochondrial health, biogenesis, and overall function. One key modulator of mitochondrial function is AMPK. Chemicals like AICAR, Metformin, and Berberine serve as AMPK activators, with AMPK being crucial for mitochondrial biogenesis and metabolic regulation. The upregulation of AMPK activity can foster mitochondrial protein expression, thereby indirectly affecting AARS2, which has a pivotal role in mitochondrial translation. Another significant axis of mitochondrial regulation is through SIRT1, a protein involved in mitochondrial function. Resveratrol is a chemical activator of SIRT1, and its activation can elevate mitochondrial protein expression, providing another route for indirect modulation of AARS2.
Further emphasis on mitochondrial health is evident through chemicals like MitoQ and α-Lipoic acid, both targeting the mitochondria to mitigate oxidative stress. Mitochondrial health is paramount for the proper function of proteins essential for mitochondrial activity, such as AARS2. Similarly, PQQ is a promoter of mitochondrial biogenesis. By augmenting the quantity and health of mitochondria, PQQ can indirectly influence the role of AARS2 in mitochondrial translation. Additionally, Coenzyme Q10 and C10, which participate in the electron transport chain and support mitochondrial function, respectively, also highlight the intricate relationship between mitochondrial well-being and the modulation of AARS2. Through these chemicals and their targeted pathways, the intricate balance of mitochondrial health and AARS2 function is underscored.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
AMPK activator. AARS2 plays a role in mitochondrial translation. AMPK activation can influence mitochondrial biogenesis and indirectly affect proteins like AARS2. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Activates SIRT1, which is involved in mitochondrial function. SIRT1 activation can enhance mitochondrial protein expression, thereby indirectly modulating AARS2 levels. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
AMPK activator. By promoting mitochondrial function and biogenesis through AMPK, Metformin can indirectly influence the levels and function of AARS2 in the mitochondria. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $92.00 $269.00 $337.00 $510.00 $969.00 | 4 | |
A precursor to NAD+. Boosting NAD+ levels can influence mitochondrial health and function, thus indirectly modulating AARS2. | ||||||
Mito-Q | 444890-41-9 | sc-507441 | 5 mg | $284.00 | ||
Targets the mitochondria to combat oxidative stress. By enhancing mitochondrial health, MitoQ can indirectly sustain or upregulate proteins like AARS2 that are crucial for mitochondrial function. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Activates AMPK. Berberine's influence on AMPK and subsequently on mitochondrial biogenesis can indirectly modulate AARS2 expression and function. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $70.00 $180.00 | 1 | |
Acts to improve mitochondrial function by participating in the electron transport chain. Enhanced mitochondrial function can indirectly promote the expression and function of mitochondrial proteins, including AARS2. | ||||||
Spermidine | 124-20-9 | sc-215900 sc-215900B sc-215900A | 1 g 25 g 5 g | $56.00 $595.00 $173.00 | ||
Autophagy inducer which can improve mitochondrial quality. Improved mitochondrial health can support the function of mitochondrial proteins like AARS2. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Acts as an antioxidant in mitochondria. Enhanced mitochondrial health through reduced oxidative stress can indirectly support proteins essential for mitochondrial function, such as AARS2. | ||||||
Pyrroloquinoline quinone | 72909-34-3 | sc-210178 | 1 mg | $238.00 | ||
Promotes mitochondrial biogenesis. By increasing the number and health of mitochondria, PQQ can indirectly influence the expression and function of proteins integral to mitochondrial translation, like AARS2. | ||||||