PDGFR Inhibitors

Santa Cruz Biotechnology now offers a broad range of PDGFR Inhibitors. The biological effects of Platelet-derived growth factor (PDGF) proteins are mediated via two tyrosine kinase receptors, PDGFR-α and PDGFR-β. PDGF-mediated signaling is critical for development of many organ systems and is important for growth and survival. PDGFR Inhibitors offered by Santa Cruz inhibit PDGFR and, in some cases, other development and tyrosine kinase receptor related proteins. View detailed PDGFR Inhibitor specifications, including PDGFR Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Imatinib mesylate
Imatinib mesylate is a c-Abl, PDGFR, and c-kit inhibitor that halts chronic myelogenous leukemia related growth.
220127-57-1 sc-202180
sc-202180A
25 mg
100 mg
$37.00
$101.00
48
(1)
Imatinib
Imatinib is an inhibitor of multiple tyrosine kinases
152459-95-5 sc-267106
10 mg
$203.00
18
(1)
Tyrphostin A23
Tyrphostin A23 is an agent that blocks EGF-dependent autophosphorylation
118409-57-7 sc-3554
10 mg
$79.00
13
(1)
Tyrphostin AG 1295
Tyrphostin AG 1295 is a selective inhibitor of platelet-derived growth factor (PDGF) tyrosine receptor kinase
71897-07-9 sc-3558
sc-3558A
5 mg
25 mg
$95.00
$255.00
9
(1)
Tyrphostin 9
Tyrphostin 9 is a PDGFR and calcium inhibitor
10537-47-0 sc-200568
sc-200568A
50 mg
250 mg
$72.00
$276.00
1
(1)
AG 494
AG 494 is a potent and selective inhibitor of EGFR tyrosine kinase
133550-35-3 sc-202043
sc-202043A
10 mg
50 mg
$69.00
$255.00
0
(1)
Masitinib
Masitinib is A tyrosine kinase, c-Kit, PDGFR, FGFR3, and FAK pathway inhibitor
790299-79-5 sc-211777
10 mg
$130.00
0
(0)
AP 24534
AP 24534 is a Bcr-Abl (Bcr and c-Abl fusion), FGFR, and Flk-1 inhibitor
943319-70-8 sc-362710
sc-362710A
10 mg
50 mg
$169.00
$945.00
1
(1)
Motesanib Diphosphate
Motesanib Diphosphate is an ATP-competitive inhibitor
857876-30-3 sc-364541
sc-364541A
5 mg
10 mg
$255.00
$480.00
0
(0)
DMPQ dihydrochloride
DMPQ dihydrochloride is a potent and selective inhibitor of PDGFRβ tyrosine kinase
137206-97-4 sc-203927
sc-203927A
10 mg
50 mg
$150.00
$605.00
0
(0)
Oxindole I
Oxindole I is a potent, selective inhibitor of VEGF
sc-222104
10 mg
$268.00
2
(0)
AG-370
AG-370 is a selective inhibitor of PDGFR kinase
134036-53-6 sc-205203
sc-205203A
1 mg
10 mg
$90.00
$392.00
0
(0)
RG-13022
RG-13022 is an inhibitor of the EGF and PDGF receptor tyrosine kinases
136831-48-6 sc-200591
sc-200591A
5 mg
10 mg
$95.00
$175.00
1
(0)
AG-1296
AG-1296 is a potent inhibitor of PDGFR kinase and c-Kit
146535-11-7 sc-200631
sc-200631A
5 mg
25 mg
$117.00
$458.00
5
(1)
3-(4-Isopropylbenzylidenyl)shyindolin-2-one
3-(4-Isopropylbenzylidenyl)indolin-2-one is a non-selective inhibitor of RTKs
186611-55-2 sc-202413
sc-202413A
1 mg
5 mg
$39.00
$206.00
0
(0)
PP121
PP121 is an inhibitor of c-Abl, PI 3-kinase, PDGFR, Hck, FRAP, Flk-1, SRC, and DNA-PK
1092788-83-4 sc-301605
5 mg
$139.00
1
(0)
PDGFRbeta/RAF Kinase Inhibitor
PDGFRβ/RAF Kinase Inhibitor is a potent inhibitor
sc-364570
10 mg
$319.00
0
(0)
PDGFR Tyrosine Kinase Inhibitor I
PDGFR Tyrosine Kinase Inhibitor I is a cell-permeable and selective, ATP-competitive inhibitor of PDGFR tyrosine kinase
sc-222142
1 mg
$190.00
0
(0)
PDGFR Tyrosine Kinase Inhibitor II
PDGFR Tyrosine Kinase Inhibitor II is a cell-permeable isothiourea compound that perturbs MreB function
249762-74-1 sc-204172
1 mg
$232.00
0
(0)
Sunitinib Malate
Sunitinib Malate is an antineoplastic agent, Flk-1 inhibitor, and ATP-competitve inhibitor of PDGFRβ
341031-54-7 sc-220177
sc-220177A
sc-220177B
10 mg
100 mg
3 g
$179.00
$450.00
$1,000.00
4
(1)
AGL 2043
AGL 2043 is a cell permeable compound that acts as a potent inhibitor of type III receptor tyrosine kinases
22617-28-8 sc-203808
1 mg
$295.00
0
(1)
SU 16f
SU 16f is a potent PDGFRβ inhibitor
251356-45-3 sc-204307
sc-204307A
10 mg
50 mg
$214.00
$880.00
0
(0)
PDGFR Tyrosine Kinase Inhibitor IV
PDGFR Tyrosine Kinase Inhibitor IV is an indenopyrazole agent that displays potent antiproliferative properties
627518-40-5 sc-205794
sc-205794A
sc-205794B
sc-205794C
1 mg
5 mg
10 mg
50 mg
$26.00
$135.00
$252.00
$1,105.00
1
(0)
PD 166285
PD 166285 is an inhibitor of RTK, c-Src, FGFR1, Wee 1, and PDGFRβ
212391-63-4 sc-208153
5 mg
$100.00
1
(1)
PDGFR Tyrosine Kinase Inhibitor III
PDGFR Tyrosine Kinase Inhibitor III is an ATP-competitive PDGFR inhibitor
205254-94-0 sc-204173
1 mg
$156.00
2
(1)
VEGFR2 Kinase Inhibitor III
VEGFR2 Kinase Inhibitor III is a VEGFR2, Met, RET, PDGFR, and ALK inhibitor
204005-46-9 sc-202851
5 mg
$77.00
4
(1)
Pazopanib Hydrochloride
Pazopanib Hydrochloride is a multi-targeted inhibitor
635702-64-6 sc-364564
sc-364564A
10 mg
25 mg
$105.00
$225.00
1
(1)
Pazopanib
Pazopanib is a potent and selective inhibitor of Flk-1, PDGFR and c-kit
444731-52-6 sc-396318
sc-396318A
25 mg
50 mg
$120.00
$170.00
1
(1)
PD 161570
PD 161570 is a selective FGFR inhibitor
192705-80-9 sc-361284
sc-361284A
5 mg
25 mg
$112.00
$446.00
0
(0)
Sorafenib
Sorafenib is an inhibitor of Raf-1 and B-RAF as well as several tyrosine kinases. Sorafenib also inhibits tumor angiogenesis by inducing tumor cell apopt
284461-73-0 sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
$50.00
$250.00
$400.00
79
(2)
FGF Receptor Tyrosine Kinase Inhibitor IV, NP603
FGF Receptor Tyrosine Kinase Inhibitor IV, NP603 is a SU6668 derivative that inhibits the kinase activity of PDGFRβ, FGFR1 and VEGFR2
sc-221613
5 mg
$220.00
0
(0)
Dovitinib, Free Base
Dovitinib, Free Base is the free base form of an FGFR inhibitor
405169-16-6 sc-396771
sc-396771A
10 mg
25 mg
$170.00
$350.00
0
(0)
Amuvatinib
Amuvatinib is a multi-targeted tyrosine kinase inhibitor of PDGF and c-Kit
850879-09-3 sc-364402
sc-364402A
5 mg
10 mg
$379.00
$500.00
0
(0)
BIBF1120
BIBF1120 is BIBF1120 is a potent kinase inhibitor found to affect VEGF, PDGF, and FGF receptors
656247-17-5 sc-364433
sc-364433A
5 mg
10 mg
$180.00
$315.00
0
(0)
Crenolanib
Crenolanib is a selective inihibitor of PDGFRα
670220-88-9 sc-364470
sc-364470A
5 mg
10 mg
$309.00
$437.00
0
(1)
4,4prime-Bis(4-aminophenoxy)biphenyl
4,4′-Bis(4-aminophenoxy)biphenyl is a potent Flk-1 (VEGFR2) and Tie-2 inhibitor
13080-85-8 sc-267771
5 g
$100.00
0
(0)

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