Date published: 2025-11-1

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9930104L06Rik Activators

Chemical activators of the AFG2 interacting ribosome maturation factor play significant roles in the modulation of ribosome assembly and function. Guanosine-5'-triphosphate (GTP) is one such activator, initiating a cascade of G-protein signaling events that eventually lead to the activation of this factor, thereby promoting ribosome biogenesis and function. Similarly, magnesium chloride acts as a cofactor that is essential for the structural integrity and proper function of ribosomal assembly. The presence of magnesium ions ensures that the ribosome structure is maintained in a state that is conducive to the AFG2 interacting ribosome maturation factor's involvement in maturation processes.

Furthermore, potassium chloride contributes to cellular homeostasis, optimizing conditions for the AFG2 interacting ribosome maturation factor to facilitate its role in ribosome assembly. Sodium orthovanadate, by inhibiting phosphatases, ensures that phosphorylation states of proteins involved in ribosome assembly are maintained, which in turn, supports the activation state of the AFG2 interacting ribosome maturation factor. Ammonium sulfate affects protein solubility and stability, which can have an enabling effect on the factor's activity. Trace elements such as manganese(II) chloride and zinc sulfate contribute to the activation of the AFG2 interacting ribosome maturation factor by serving as cofactors for enzymes and RNA polymerases, respectively, both of which are crucial in the process of ribosome maturation. The amino acid L-Histidine can also instigate signaling pathways connected to protein synthesis, where the AFG2 interacting ribosome maturation factor has a significant role. Heavy metals like cadmium chloride, cobalt(II) chloride, nickel(II) chloride, and copper(II) sulfate can affect various cellular pathways that ultimately influence the AFG2 interacting ribosome maturation factor's role in ribosome biogenesis and function, albeit these interactions are complex and multifaceted, often involving cellular stress responses and metal homeostasis mechanisms.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Guanosine-5′-Triphosphate, Disodium salt

86-01-1sc-507564
1 g
$700.00
(0)

Guanosine-5′-triphosphate (GTP) activates G-proteins which are involved in signaling pathways that can lead to the activation of the AFG2 interacting ribosome maturation factor by promoting ribosome biogenesis and function, which is crucial for its activity.

Magnesium chloride

7786-30-3sc-255260C
sc-255260B
sc-255260
sc-255260A
10 g
25 g
100 g
500 g
$27.00
$34.00
$47.00
$123.00
2
(1)

Magnesium chloride can activate the AFG2 interacting ribosome maturation factor by serving as a cofactor necessary for the proper functioning of ribosomal assembly, which is a process that the protein is involved with.

Potassium Chloride

7447-40-7sc-203207
sc-203207A
sc-203207B
sc-203207C
500 g
2 kg
5 kg
10 kg
$25.00
$56.00
$104.00
$183.00
5
(1)

Potassium chloride can influence ionic balance and cellular homeostasis, which indirectly activates the AFG2 interacting ribosome maturation factor by optimizing conditions for ribosome assembly where the protein has a role.

Sodium Orthovanadate

13721-39-6sc-3540
sc-3540B
sc-3540A
5 g
10 g
50 g
$45.00
$56.00
$183.00
142
(4)

Sodium orthovanadate is a phosphatase inhibitor that can lead to activation of the AFG2 interacting ribosome maturation factor by preventing dephosphorylation of proteins that are involved in ribosome assembly and function.

Ammonium Sulfate

7783-20-2sc-29085A
sc-29085
sc-29085B
sc-29085C
sc-29085D
sc-29085E
500 g
1 kg
2 kg
5 kg
10 kg
22.95 kg
$10.00
$20.00
$30.00
$40.00
$60.00
$100.00
9
(1)

Ammonium sulfate can contribute to the activation of the AFG2 interacting ribosome maturation factor by altering the protein solubility and stability, facilitating its role in ribosome maturation processes.

Manganese(II) chloride beads

7773-01-5sc-252989
sc-252989A
100 g
500 g
$19.00
$30.00
(0)

Manganese(II) chloride can activate the AFG2 interacting ribosome maturation factor by acting as a cofactor for enzymes that are involved in the maturation of ribosomes, a process that the protein directly participates in.

L-Histidine

71-00-1sc-394101
sc-394101A
sc-394101B
sc-394101C
sc-394101D
25 g
100 g
250 g
500 g
1 kg
$53.00
$82.00
$185.00
$200.00
$332.00
1
(0)

L-Histidine can activate the AFG2 interacting ribosome maturation factor through histidine kinase signaling pathways that are implicated in protein synthesis and ribosome assembly, processes that the protein is known to be involved in.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zinc sulfate can activate the AFG2 interacting ribosome maturation factor by serving as an essential trace element for the function of RNA polymerases, which indirectly aids the protein's role in ribosome maturation.

Cadmium chloride, anhydrous

10108-64-2sc-252533
sc-252533A
sc-252533B
10 g
50 g
500 g
$55.00
$179.00
$345.00
1
(1)

Cadmium chloride can indirectly activate the AFG2 interacting ribosome maturation factor by influencing cellular stress pathways that lead to the upregulation of ribosome assembly processes in which the protein plays a part.

Cobalt(II) chloride

7646-79-9sc-252623
sc-252623A
5 g
100 g
$63.00
$173.00
7
(1)

Cobalt(II) chloride can activate the AFG2 interacting ribosome maturation factor by inducing hypoxic-like responses that can upregulate ribosomal biogenesis and thereby facilitate the protein's function in ribosome assembly.