Date published: 2025-9-6

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TARDBP 抗体 (41-7.1): sc-100871

4.2(5)
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说明书
  • TARDBP抗体(41-7.1)是小鼠单克隆IgG1 κ, 在6篇文献中引用,规格为100 µg/ml
  • 免疫human物种的重组TARDBP
  • 推荐用于 human 来源的TARDBP WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取TARDBP (41-7.1): sc-100871免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成TARDBP 抗体 (41-7.1)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

TARDBP抗体(41-7.1)是一种IgG1 κ小鼠单克隆TARDBP抗体,能够通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、免疫组化(IHC,P)和酶联免疫吸附试验(ELISA)检测人源的TARDBP。TARDBP抗体(41-7.1)以非偶联的抗TARDBP抗体形式提供。TARDBP(TAR DNA结合蛋白),也被称为TDP-43,是一种含有两个RRM(RNA识别基序)结构域的核蛋白。它在各种组织中普遍表达,在胎盘、肺、胰腺、脾脏和生殖道中的表达水平最高。TARDBP作为DNA结合蛋白发挥作用,并特异性地结合到HIV的TAR DNA序列基序上。通过与TAR基序的这种关联,TARDBP作为转录抑制因子并抑制HIV-1的转录。TARDBP还可以作为剪接活性的负调节因子,已知参与CFTR(囊性纤维化跨膜受体)的剪接。此外,TARDBP是泛素阳性包涵体的主要成分,在许多神经退行性疾病中都很突出。这表明TARDBP可能在神经退行性疾病的发展中发挥作用。由于存在选择性剪接事件,TARDBP存在各种异构体。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

TARDBP 抗体 (41-7.1)

sc-100871
100 µg/ml
$333.00

Can sc-100871: TARDBP (41-7.1) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: jerojero
Thank you for your question. Yes, sc-100871: TARDBP (41-7.1) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2023-05-29
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Rated 4 out of 5 by from this work in ICCI have used this antibody on immunocytochemistry and worked well.
Date published: 2017-09-19
Rated 5 out of 5 by from Excellent choice for TARDP detection!Strong and specific antibody for TARDBP, gives great data in WB, IHC and in IF. Smart choice!
Date published: 2017-01-25
Rated 4 out of 5 by from Works very well both both non transfectedWorks very well both both non transfected and transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-07-19
Rated 4 out of 5 by from Produced wonderful immunoperoxidase nuclearProduced wonderful immunoperoxidase nuclear staining in formalin-fixed, paraffin-embedded human leiomyosarcoma tissue. -SCBT QC
Date published: 2015-03-16
Rated 4 out of 5 by from WB: CrispWB: Crisp, clean band in A-431 whole cell lysate. -SCBT QC
Date published: 2015-02-03
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TARDBP 抗体 (41-7.1) is rated 4.2 out of 5 by 5.
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