OSBP2 Antibody (G-8): sc-365951
- OSBP2 Antibody (G-8) is a mouse monoclonal IgM provided at 200 µg/ml
- specific for an epitope mapping between amino acids 479-507 within an internal region of OSBP2 of mouse origin
- recommended for detection of OSBP2 of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for OSBP2 Antibody (G-8). This work is in progress.
QUICK LINKS
OSBP2 Antibody (G-8) is a mouse monoclonal IgM antibody that detects OSBP2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). OSBP2, a member of the oxysterol-binding protein family, plays a crucial role in lipid metabolism and cellular signaling, particularly in the transport of sterols from lysosomes to the nucleus. This transport is vital as OSBP2 regulates the expression of key genes involved in cholesterol synthesis, including HMG synthetase, HMG-CoA reductase, and the low-density lipoprotein receptor (LDLR). OSBP2 localizes primarily in the testis, retina, and fetal liver, highlighting OSBP2′s importance in specific tissues where lipid metabolism is critical for development and function. Additionally, OSBP2′s interaction with 25-hydroxy-cholesterol, a potent modulator of cholesterol synthesis gene transcription, underscores OSBP2′s role in maintaining cellular cholesterol homeostasis. Anti-OSBP2 antibody (G-8) enables researchers to gain insights into the regulatory mechanisms of lipid metabolism and the implications of dysregulated cholesterol levels in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
OSBP2 Antibody (G-8) | sc-365951 | 200 µg/ml | $322.00 | |||
OSBP2 (G-8) Neutralizing Peptide | sc-365951 P | 100 µg/0.5 ml | $69.00 |