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Moesin 抗体 (38/87): sc-58806

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说明书
  • Moesin抗体(38/87)是小鼠单克隆IgG1 κ, 在9篇文献中引用,规格为200 µg/ml
  • 免疫bovine物种的Moesin
  • 推荐用于 mouse, rat 和 human 来源的Moesin WB, IP, IF 和 IHC(P)检测; 也和以下物种反应,包括: 和 bovine and porcine; 不会与 talin or ezrin产生交联反应
  • 看 Moesin (E-10): sc-13122,可查看有标记的 Moesin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgGκ BP-HRP是Moesin Antibody (38/87) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。该试剂现可与Moesin Antibody (38/87) 搭配使用(请参阅下面的订购信息)。有关其它 m-IgGκ BP 结合物,请参阅我们完整的小鼠 IgG 结合蛋白列表。
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関連項目

Ezrin、Moesin和Radixin属于高同源肌动蛋白相关蛋白家族,仅位于质膜之下。这些蛋白质被认为参与介导细胞骨架和膜蛋白之间的相互作用。Ezrin是各种蛋白酪氨酸激酶的主要细胞质底物,包括表皮生长因子受体。Ezrin也被鉴定为cAMP依赖性蛋白激酶(A激酶)锚定蛋白,并被命名为AKAP78。Moesin和Radixin与Ezrin具有70%以上的同源性,并在各种细胞类型中共同表达。尽管同源性很高,但这三种蛋白质表现出独特的受体特异性磷酸化模式。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Moesin 抗体 (38/87) 参考文献:

  1. Moesin调节体内中性粒细胞的滚动速度。  |  Matsumoto, M. and Hirata, T. 2016. Cell Immunol. 304-305: 59-62. PMID: 27131737
  2. 肌球蛋白、Src和ROS在晚期糖基化终产物诱导的血管内皮功能障碍中的作用。  |  Zhang, WJ., et al. 2017. Microcirculation. 24: PMID: 28129474
  3. Moesin,Ezrin/Radixin/Moesin家族成员,可调节肝纤维化。  |  Karvar, S., et al. 2020. Hepatology. 72: 1073-1084. PMID: 31860744
  4. ERM蛋白moesin调节体内自然杀伤细胞的稳态。  |  Satooka, H., et al. 2022. Cell Immunol. 371: 104456. PMID: 34798556
  5. 肿瘤代谢产物乳酸通过调节MOESIN的乳化和增强调节性T细胞中的TGF-β信号传导来促进肿瘤发生。  |  Gu, J., et al. 2022. Cell Rep. 40: 111122. PMID: 35858574
  6. Moesin在调节肥大细胞分泌中的潜在作用。  |  Theoharides, TC. and Kempuraj, D. 2023. Int J Mol Sci. 24: PMID: 37569454
  7. 莫埃辛在诊断和评估淋巴管平滑肌瘤病严重程度中的作用。  |  Song, X., et al. 2024. Respir Res. 25: 57. PMID: 38267973
  8. Moesin缺乏导致狼疮样肾炎,并伴有CXCL13产生巡逻单核细胞的积累。  |  Ichioka, S., et al. 2024. Biochem Biophys Res Commun. 712-713: 149943. PMID: 38640733
  9. Moesin控制细胞融合和破骨细胞功能。  |  Dufrancais, O., et al. 2024. bioRxiv.. PMID: 38798563
  10. Ezrin、radixin和moesin对于巨噬细胞迁移和细胞皮质力学是不可或缺的  |  Verdys, P., et al. 2024. EMBO J. 43: 4822-4845. PMID: 39026000

订购信息

产品名称产品编号规格价格数量收藏夹

Moesin 抗体 (38/87)

sc-58806
200 µg/ml
$322.00

Moesin (38/87): m-IgGκ BP-HRP 套装

sc-551068
200 µg Ab; 40 µg BP
$361.00

We are using Moesin Antibody (38/87): sc-58806 and would like to know which domain of the moesin protein it recognizes. Thanks!

Asked by: LilyP
Thank you for your question. The exact epitope recognized by this mouse monoclonal antibody has not yet been determined.
Answered by: Technical Support
Date published: 2019-04-25

I am using Moesin (38/87): sc-58806 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: jenniferc
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by FL from Strong band in WB in HeLaStrong band in WB in HeLa, ECV304 and Jurkat whole cell lysates. -SCBT QC
Date published: 2015-06-16
Rated 5 out of 5 by JM from Good publishable data in WB and IF in rabbitGood publishable data in WB and IF in rabbit intestine. -SCBT Publication Review
Date published: 2015-06-08
Rated 5 out of 5 by JL from Good specificity in WB in human transfectedGood specificity in WB in human transfected 293T and A-431 whole cell lysates. -SCBT QC
Date published: 2015-06-05
Rated 5 out of 5 by FL from Published for WB in human Bone marrow andPublished for WB in human Bone marrow and PB samples. -SCBT Publication Review
Date published: 2015-04-22
Rated 5 out of 5 by MS from Good staining in IF in human HeLa cellsGood staining in IF in human HeLa cells. -SCBT Publication Review
Date published: 2015-03-08
Rated 5 out of 5 by HC from Beautiful immunoperoxidase cytoplasmic andBeautiful immunoperoxidase cytoplasmic and membrane staining in formalin fixed, paraffin-embedded human tonsil tissue. -SCBT QC
Date published: 2015-02-09
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Moesin 抗体 (38/87) is rated 5.0 out of 5 by 6.
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