Date published: 2026-10-17
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KIR6.2 Antibody (B-9) - Western Blotting - Image 416256
抗体 近红外西式印迹分析 KIR6.2 在 HeLa (A)、Hep G2 (B)、MCF7 (C)、MIA PaCa-2 (D) 和 3T3-L1 (E) 细胞总裂解液中的表达。使用的检测试剂：m-IgG2a BP-CFL 790：sc-542740。使用UltraCruz®阻断试剂进行阻断：sc-516214。
抗体 近红外西式印迹分析 KIR6.2 在 HeLa (A)、Hep G2 (B)、MCF7 (C)、MIA PaCa-2 (D) 和 3T3-L1 (E) 细胞总裂解液中的表达。使用的检测试剂：m-IgG2a BP-CFL 790：sc-542740。使用UltraCruz®阻断试剂进行阻断：sc-516214。

KIR6.2 抗体 (B-9): sc-390104

5.0(7)
寫評論提問
说明书
  • KIR6.2抗体(B-9)是小鼠单克隆IgG2a λ KIR6.2抗体, 在12篇文献中引用，规格为200 µg/ml
  • 特异性抗原位于human物种的KIR6.2的内部区域内的氨基酸301-337之间
  • KIR6.2 抗体 (B-9) 推荐用于WB, IP, IF, IHC(P) 和 ELISA ，检测 mouse, rat, human 和 来源的KIR6.2; 也和以下物种反应，包括： 和 equine, canine, bovine and avian
  • 抗KIR6.2抗体（B-9）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 2a BP-HRP">m-IgG2a BP-HRP和m-IgGλ BP-HRP是KIR6.2 Antibody (B-9) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与KIR6.2 Antibody (B-9) 打包提供（请参阅下面的订购信息）。
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関連項目

附加KIR抗体，包括KIR3.1, KIR3.4, KIR4.1, KIR4.2, KIR6.2和KIR7.1

KIR6.2抗体（B-9）是一种IgG2a λ小鼠单克隆KIR6.2抗体（也称为KCNJ11抗体或BIR抗体），可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人源的KIR6.2蛋白。KIR6.2抗体（B-9）可以以非偶联抗KIR6.2抗体的形式提供，也可以以多种偶联形式的抗KIR6.2抗体提供，包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。ATP敏感性K+通道通过将细胞代谢与电活动相结合，在许多细胞功能中发挥重要作用。KIR6.1和KIR6.2是KIR（内向整流钾通道）家族钾通道的成员。内向整流K+通道具有更大的允许钾流入细胞而不是流出细胞的趋势。这些通道由两个亚基组成：一个KIR6.0亚家族成分和一个SUR成分，SUR是ATP结合盒蛋白超家族的成员。编码这些通道的基因突变是常染色体隐性遗传病的原因，其特征是胰岛素分泌不受调节。KIR通道亚基的氨基末端和羧基末端结构域均位于细胞内，KIR6.2的两个细胞内结构域在物理上相互作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

KIR6.2 抗体 (B-9) 参考文献:

  1. ATP 敏感钾通道：结构, 功能和病理生理学。  |  Inagaki, N. and Seino, S. 1998. Jpn J Physiol. 48: 397-412. PMID: 10021494
  2. ATP 敏感钾通道：异多聚体钾通道/受体组装模型。  |  Seino, S. 1999. Annu Rev Physiol. 61: 337-62. PMID: 10099692
  3. 分泌胰岛素的胰岛β细胞中对 ATP 敏感的 K+ 通道的结构和功能。  |  Miki, T., et al. 1999. J Mol Endocrinol. 22: 113-23. PMID: 10194514
  4. 先天性高胰岛素血症：一种异质性疾病的分子基础。  |  Meissner, T., et al. 1999. Hum Mutat. 13: 351-61. PMID: 10338089
  5. 绘制内向整流钾通道 Kir6.2 细胞内结构域之间的物理相互作用图。  |  Tucker, SJ. and Ashcroft, FM. 1999. J Biol Chem. 274: 33393-7. PMID: 10559219
  6. 模拟Kir6.2通道中PIP2诱导的开关转换。  |  Bründl, M., et al. 2021. Front Mol Biosci. 8: 711975. PMID: 34447786
  7. Kir6.2对通过调节PM20D1减少的线粒体ATP生成来维持神经元特征至关重要。  |  Song, N., et al. 2021. Redox Biol. 47: 102168. PMID: 34673451
  8. Kir6.2缺陷小鼠在外周神经中表现出躯体感觉功能障碍和轴突丢失。  |  Nakai-Shimoda, H., et al. 2022. iScience. 25: 103609. PMID: 35005553
  9. 开放型KATP通道的结构揭示了串联的PIP2结合位点，介导了Kir6.2和SUR1的调节界面。  |  Driggers, CM., et al. 2024. Nat Commun. 15: 2502. PMID: 38509107
  10. Kir6.2变体的分子动力学模拟揭示了与糖尿病的潜在关联。  |  Elangeeb, ME., et al. 2024. Molecules. 29: PMID: 38675722
  11. IKATP 的重组：内向整流亚基加磺酰脲受体。  |  Inagaki, N., et al. 1995. Science. 270: 1166-70. PMID: 7502040
  12. 内向整流钾通道：其分子异质性和功能。  |  Isomoto, S., et al. 1997. Jpn J Physiol. 47: 11-39. PMID: 9159640

订购信息

产品名称产品编号规格价格数量收藏夹

KIR6.2 抗体 (B-9)

sc-390104
200 µg/ml
$322.00

KIR6.2 (B-9): m-IgGλ BP-HRP 套装

sc-523404
200 µg Ab, 40 µg BP
$361.00

KIR6.2 (B-9): m-IgG2a BP-HRP 套装

sc-546237
200 µg Ab; 10 µg BP
$361.00

KIR6.2 抗体 (B-9) AC

sc-390104 AC
500 µg/ml, 25% agarose
$424.00

KIR6.2 抗体 (B-9) HRP

sc-390104 HRP
200 µg/ml
$322.00

KIR6.2 抗体 (B-9) FITC

sc-390104 FITC
200 µg/ml
$336.00

KIR6.2 抗体 (B-9) PE

sc-390104 PE
200 µg/ml
$349.00

KIR6.2 抗体 (B-9) Alexa Fluor® 488

sc-390104 AF488
200 µg/ml
$364.00

KIR6.2 抗体 (B-9) Alexa Fluor® 546

sc-390104 AF546
200 µg/ml
$364.00

KIR6.2 抗体 (B-9) Alexa Fluor® 594

sc-390104 AF594
200 µg/ml
$364.00

KIR6.2 抗体 (B-9) Alexa Fluor® 647

sc-390104 AF647
200 µg/ml
$364.00

KIR6.2 抗体 (B-9) Alexa Fluor® 680

sc-390104 AF680
200 µg/ml
$364.00

KIR6.2 抗体 (B-9) Alexa Fluor® 790

sc-390104 AF790
200 µg/ml
$364.00

KIR6.2 (B-9) 中和勝肽

sc-390104 P
100 µg/0.5 ml
$69.00

What is the scendary antibody? Rabit anti-mouse IgG? or Goat anti-mouse IgG? I can wait your answer. Thanks

Asked by: dkfma1143
Thank you for your question. You can use any anti-mouse secondary antibody with this mouse monoclonal primary antibody. Please contact our Technical Service Department by phone, e-mail or live chat if you have any further questions. Alternatively, you can contact your local distributor: https://www.scbt.com/scbt/resources/distributors
Answered by: Tech Service
Date published: 2017-06-26

Can the peptide sc-390104 P be used in Western Blot as a positive control?

Asked by: AbPolly
Thank you for your question. The blocking peptide sc-390104 P is a short synthetic peptide intended for use as a negative control by preadsorption. It is not appropriate for use as a positive control in Western Blot.
Answered by: Technical Support 3
Date published: 2017-02-09
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Rated 5 out of 5 by UCDS from Good resultsKir6.2(B-9)antibody Works good for western blot for both human and mouse atrial tissues lysate, dilution1:500, clean background and strong signal.
Date published: 2019-07-10
Rated 5 out of 5 by SJmn from Great for western blottingI've used this antibody at 1:200 dilution on mouse pancreatic islets with great results (clean specific band with no background).
Date published: 2018-02-13
Rated 5 out of 5 by leboalice from Good workingThis antibody is used for WB.The antibody incubated at RT for 1hour.No background but strong band at 50kda.I use the Hepg2 cell and loading 50ug sample.
Date published: 2017-08-12
Rated 5 out of 5 by cbx_up from good resultWe get pretty results in WB assay, with a specific band. Our samples are mouse cell , the working dilution is 1: 300.
Date published: 2017-05-27
Rated 5 out of 5 by Han Wang from 申请了10ug的试用装上个月申请了10ug的试用装，很好用，能做出sh-SY5Y细胞的全细胞蛋白。分子量在40-55marker的中间。
Date published: 2017-05-08
Rated 5 out of 5 by Cweed from It will provide specific detection.This antibody is supported by great staining and blotting data. It works well in typical lab applications and is reactive with a wide range of species.
Date published: 2017-01-27
Rated 5 out of 5 by TS from Produced positive Western blot data of KIR6Produced positive Western blot data of KIR6.2 expression in Sol8 and MIA PaCa-2 whole cell lysates and mouse brain tissue extract . -SCBT QC
Date published: 2014-04-13
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KIR6.2 抗体 (B-9) is rated 5.0 out of 5 by 7.
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