KIR Activators
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Diazoxide | 364-98-7 | sc-200980 | 1 g | $300.00 | 5 | |
Diazoxide acts as a potent modulator of ion channels, particularly influencing ATP-sensitive potassium channels. Its unique structure allows for specific interactions with the channel's binding sites, stabilizing the open conformation and altering ion permeability. This results in distinct electrophysiological responses, impacting cellular excitability and signaling pathways. The compound's kinetic profile reveals rapid association and dissociation rates, underscoring its dynamic role in cellular ion homeostasis. | ||||||
Minoxidil (U-10858) | 38304-91-5 | sc-200984 sc-200984A | 100 mg 1 g | $68.00 $344.00 | ||
Minoxidil exhibits unique properties as a potassium channel opener, characterized by its ability to enhance the flow of potassium ions across cell membranes. Its molecular structure facilitates specific binding interactions that promote channel activation, leading to alterations in membrane potential. The compound's reaction kinetics demonstrate a notable affinity for channel sites, resulting in a swift modulation of cellular excitability. This dynamic behavior contributes to its distinct influence on ion transport mechanisms. | ||||||
Nicorandil | 65141-46-0 | sc-200995 sc-200995B sc-200995A sc-200995C | 50 mg 100 mg 250 mg 1 g | $57.00 $98.00 $240.00 $500.00 | 4 | |
Nicorandil functions as a potassium channel activator, distinguished by its dual action as both a nitrate donor and a potassium channel opener. Its unique molecular architecture allows for effective interaction with specific binding sites, promoting vasodilation through enhanced potassium ion efflux. The compound's kinetics reveal a rapid onset of action, influencing cellular signaling pathways and contributing to its role in modulating vascular smooth muscle tone. This multifaceted behavior underscores its significance in ion channel dynamics. | ||||||
Levcromakalim | 94535-50-9 | sc-361230 sc-361230A | 10 mg 50 mg | $428.00 $1380.00 | 2 | |
Levcromakalim acts as a potassium channel opener, characterized by its selective interaction with ATP-sensitive potassium channels. Its unique structure facilitates the stabilization of the open state of these channels, leading to hyperpolarization of the cell membrane. This modulation of ion flow alters cellular excitability and influences various signaling cascades. The compound exhibits distinct reaction kinetics, allowing for a swift response in cellular environments, thereby impacting smooth muscle relaxation and vascular tone regulation. | ||||||
ZM 226600 | 147695-92-9 | sc-281189 sc-281189A | 10 mg 50 mg | $100.00 $348.00 | ||
ZM 226600 functions as a potent kir, exhibiting a unique affinity for specific ion channels that modulate cellular excitability. Its molecular structure enables precise interactions with the channel's binding sites, enhancing ion permeability and altering membrane potential dynamics. The compound's reaction kinetics are characterized by rapid onset and sustained effects, influencing downstream signaling pathways. Additionally, its distinct physical properties contribute to its behavior in various biochemical environments, facilitating targeted cellular responses. | ||||||