HOOK2 Antibody (E-9): sc-514700
- HOOK2 Antibody (E-9) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 674-696 at the C-terminus of HOOK2 of mouse origin
- recommended for detection of HOOK2 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HOOK2 Antibody (E-9) for WB applications. These reagents are now offered in bundles with HOOK2 Antibody (E-9) (see ordering information below).
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HOOK2 Antibody (E-9) is a mouse monoclonal IgG2a antibody that detects HOOK2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HOOK2 is a crucial member of the HOOK protein family, which plays a significant role in the spatial organization of membrane-trafficking systems by interacting with microtubules and various organelles. HOOK2 is composed of 719 amino acids and forms a homodimer, primarily through its central coiled-coil domain, which is essential for structural integrity and function. HOOK2 is involved in organelle binding, with particularly strong expression in the larynx and esophagus, suggesting a specialized role in these tissues. HOOK2′s unique localization to discrete subcellular structures, distinct from early or late endosomes, mitochondria, the Golgi complex, the endoplasmic reticulum, lysosomes, or multivesicular bodies, highlights potential importance in cellular trafficking and signaling pathways. HOOK2 has been implicated in esophageal cancer, potentially associating with proteins such as SURF1 and Zic2, which are also considered potential tumor antigens. Anti-HOOK2 antibody (E-9) serves as an invaluable tool for researchers investigating the dynamics of microtubule-associated proteins and their roles in cellular processes and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HOOK2 Antibody (E-9) | sc-514700 | 200 µg/ml | $322.00 | |||
HOOK2 Antibody (E-9): m-IgG Fc BP-HRP Bundle | sc-538686 | 200 µg Ab; 10 µg BP | $361.00 | |||
HOOK2 Antibody (E-9): m-IgGκ BP-HRP Bundle | sc-536346 | 200 µg Ab; 40 µg BP | $361.00 | |||
HOOK2 Antibody (E-9): m-IgG2a BP-HRP Bundle | sc-548377 | 200 µg Ab; 10 µg BP | $361.00 | |||
HOOK2 (E-9) Neutralizing Peptide | sc-514700 P | 100 µg/0.5 ml | $69.00 |