Date published: 2026-10-17
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CYP1A2 Antibody (16VII F10F12) - Western Blotting - Image 353445
CYP1A2 抗体 (16VII F10F12): sc-73476. 小鼠肝脏 (A) 和大鼠肝脏 (B) 组织提取物中 CYP1A2 表达的 Western 印迹分析.
CYP1A2 抗体 (16VII F10F12): sc-73476. 小鼠肝脏 (A) 和大鼠肝脏 (B) 组织提取物中 CYP1A2 表达的 Western 印迹分析.

CYP1A2 抗体 (16VII F10F12): sc-73476

3.0(1)
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说明书
  • CYP1A2抗体(16VII F10F12)是小鼠单克隆IgG1 (kappa轻链)，规格为200 µg/ml
  • 针对rat来源的肝细胞色素P4501A2
  • 推荐用于 mouse, rat 和 human 来源的CYP1A2 and, to a lesser extent, CYP1A1 WB 和 IP检测; 不建议用于检测rat CYP2A1, 2B1, 2B2, 2C6, 2C7, 2C11, 4A1, 4A2 and 4A3
  • m-IgG Fc BP-HRP和 m-IgG1 BP-HRP是CYP1A2 Antibody (16VII F10F12) for WB applications. 的首选辅助检测试剂，这些试剂现与CYP1A2 Antibody (16VII F10F12) 打包提供（请参阅下面的订购信息）。
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    描述
    基因信息
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    研究信息

    関連項目

    额外CYP抗体，包括CYP11B, CYP17A1, CYP19, CYP1A1, CYP1A2, CYP1B1, CYP24, CYP26A1, CYP27A1, CYP27B1, CYP2A6, CYP2B1, CYP2C6, CYP2D6, CYP2F1和CYP2F2

    CYP1A2，也称为细胞色素P450 1A2，是一种血红素硫醇单加氧酶，参与肝脏微粒体的NADPH依赖性电子传递途径。细胞色素P450家族的成员CYP1A2氧化脂肪酸、类固醇和外源性物质。它还参与了咪哒普利、普萘洛尔和氯氮平的代谢。CYP1A2定位于内质网膜上。它由3-甲基胆蒽、胰岛素、莫达非尼和 hyperforin 诱导，并被许多氟喹诺酮类抗生素、咖啡因、氟伏沙明和西咪替丁抑制。此外，CYP1A2参与雌激素代谢与癌症风险降低有关。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    CYP1A2 抗体 (16VII F10F12) 参考文献:

    1. CYP1A2的20个等位基因变体的功能特征。  |  Ito, M., et al. 2015. Drug Metab Pharmacokinet. 30: 247-52. PMID: 26022657
    2. CYP1A2基因型影响儿童癫痫患者卡马西平的药代动力学。  |  Djordjevic, N., et al. 2016. Eur J Clin Pharmacol. 72: 439-45. PMID: 26762380
    3. CYP1A2和烟草的相互作用：戒烟期间面临的主要药代动力学挑战。  |  Barrangou-Poueys-Darlas, M., et al. 2021. Drug Metab Rev. 53: 30-44. PMID: 33325257
    4. ADORA2A rs5760423和CYP1A2 rs762551多态性是帕金森病的危险因素。  |  Siokas, V., et al. 2021. J Clin Med. 10: PMID: 33498513
    5. CYP1A2基因型多态性影响训练有素的男性对咖啡因的无氧运动表现。  |  Minaei, S., et al. 2022. Int J Sport Nutr Exerc Metab. 32: 16-21. PMID: 34611052
    6. CYP1A2介导的培兰帕奈的代谢激活。  |  Ding, Z., et al. 2022. Chem Res Toxicol. 35: 490-498. PMID: 35200000
    7. 间歇性缺氧抑制肝CYP1a2表达并延迟氨茶碱代谢。  |  Zhang, XB., et al. 2022. Evid Based Complement Alternat Med. 2022: 2782702. PMID: 35529917
    8. 昼夜节律振荡器NPAS2调节小鼠肝脏中CYP1A2的昼夜表达和活性。  |  He, Y., et al. 2022. Biochem Pharmacol. 206: 115345. PMID: 36379250
    9. 编码CYP1A2的基因的多态性影响前列腺癌的风险和进展。  |  Vilčková, M., et al. 2023. Oncol Lett. 25: 85. PMID: 36760517
    10. CYP1A2（rs2069514和rs762551）多态性在COVID-19患者中的预后价值。  |  Bozkurt, I., et al. 2023. Balkan J Med Genet. 26: 35-42. PMID: 37576788

    订购信息

    产品名称产品编号规格价格数量收藏夹

    CYP1A2 抗体 (16VII F10F12)

    sc-73476
    200 µg/ml
    		$322.00

    CYP1A2 (16VII F10F12): m-IgG Fc BP-HRP 套装

    sc-553122
    200 µg Ab; 10 µg BP
    		$361.00

    CYP1A2 (16VII F10F12): m-IgG1 BP-HRP 套装

    sc-553123
    200 µg Ab; 20 µg BP
    		$361.00

    How much sample do you recommend loading on the gel for Western blot detection using CYP1A2 (16VII F10F12): sc-73476?

    Asked by: Cweed
    We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 3 out of 5 by LF from Worked with mouse transfected lysate by WBWorked with mouse transfected lysate by WB -SCBT QC
    Date published: 2013-05-21
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    CYP1A2 抗体 (16VII F10F12) is rated 3.0 out of 5 by 1.
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