SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Phenacetin | 62-44-2 | sc-257998 sc-257998A | 50 g 250 g | $48.00 $91.00 | 3 | |
Phenacetin exhibits unique interactions with CYP1A2, primarily through hydrogen bonding and hydrophobic interactions that enhance substrate affinity. Its aromatic structure allows for effective π-π interactions, influencing the enzyme's conformational dynamics. The compound's metabolic pathway is characterized by its biotransformation, which can generate reactive metabolites, potentially impacting downstream signaling pathways. This behavior underscores its role in modulating enzymatic activity and metabolic flux. | ||||||
(R)-(+)-Warfarin | 5543-58-8 | sc-255498 | 5 mg | $627.00 | ||
(R)-(+)-Warfarin interacts with CYP1A2 through specific steric and electronic effects, facilitating its metabolism. The compound's chiral nature influences binding affinity, leading to distinct enantioselective pathways. Its planar structure promotes π-π stacking interactions, which can stabilize enzyme-substrate complexes. The reaction kinetics reveal a complex interplay of competitive inhibition and allosteric modulation, affecting the overall metabolic profile and influencing the enzyme's catalytic efficiency. | ||||||