Date published: 2025-9-10

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CEACAM5/6 抗体 (By114): sc-20059

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说明书
  • CEACAM5/6抗体(By114)是小鼠单克隆IgG1 κ, 在1篇文献中引用,规格为200 µg/ml
  • 针对human B细胞淋巴瘤
  • 推荐用于 human 来源的CEACAM5 and CEACAM6 WB, IP, IF, IHC(P) 和 ELISA检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 CEACAM5 (CI-P83-1): sc-23928,可查看有标记的 CEACAM5/6 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 CEACAM5/6 抗体 (By114) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与CEACAM5/6 抗体 (By114) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

CD66(也称为癌胚抗原、CEA、胆道糖蛋白I、BGP-1、CEACAM)免疫球蛋白超家族基因编码细胞粘附蛋白,这些蛋白在肿瘤组织中的表达水平高于正常组织。CD66 mRNA在原发性结肠肿瘤中强表达,在正常结肠组织中的表达程度较低。人类CD66基因家族是一组由29个基因组成的多种上皮和造血系糖蛋白,这些基因定位于染色体19q13.1-q13.2的位置。CD66A、CD66B、CD66C、CD66D、CD66E和CD66F是特征最为明显的CD66抗原,CD66A-D的表达在刺激后在粒细胞表面上调。CD66同种型独立于细胞类型介导同型和异型细胞间粘附事件。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CEACAM5/6 抗体 (By114) 参考文献:

  1. SAR408701的临床前活性:一种新型抗CEACAM5-马钱子素抗体-药物偶联物,用于治疗CEACAM5阳性上皮肿瘤。  |  Decary, S., et al. 2020. Clin Cancer Res. 26: 6589-6599. PMID: 33046521
  2. 哮喘患者中CEACAM5水平升高。  |  Xu, C., et al. 2022. Int Arch Allergy Immunol. 183: 673-681. PMID: 35172310
  3. CEACAM6作为COPD中促进HO-1介导的抗氧化防御的新治疗靶点。  |  Wu, CY., et al. 2023. Am J Respir Crit Care Med. 207: 1576-1590. PMID: 37219322
  4. 一种新型靶向CEACAM5的人源单域抗体-药物偶联物在体外和体内均表现出强大的抗肿瘤活性。  |  Zhu, XY., et al. 2024. Acta Pharmacol Sin. 45: 609-618. PMID: 38030799
  5. NILK-2301是一种新型CEACAM5xCD3和κλ双特异性抗体,用于表达CEACAM5的癌症的免疫治疗。  |  Seckinger, A., et al. 2023. J Hematol Oncol. 16: 117. PMID: 38087365
  6. CT109-SN-38是一种新型抗体-药物偶联物,对CEACAM5和6具有双重特异性,可有效杀死胰腺癌细胞。  |  Cardenas, KCA., et al. 2024. Curr Cancer Drug Targets. 24: 720-732. PMID: 38178674
  7. CEACAM5和TROP2定义了人类胃窦癌前病变和肿瘤的化生和异型增生转变。  |  Jang, B., et al. 2024. Gastric Cancer. 27: 263-274. PMID: 38221567
  8. 对68种结直肠癌细胞系进行表型筛选,发现CEACAM6和CEACAM5是耐酸性的标志物。  |  Michl, J., et al. 2024. Proc Natl Acad Sci U S A. 121: e2319055121. PMID: 38502695
  9. 转移性前列腺癌中TROP2、CEACAM5和DLL3的评估:表达图谱和分子相关性。  |  Ajkunic, A., et al. 2024. NPJ Precis Oncol. 8: 104. PMID: 38760413
  10. 雄激素受体阴性前列腺癌中CEACAM5靶向免疫PET。  |  Imberti, C., et al. 2024. J Nucl Med. 65: 1043-1050. PMID: 38782457

订购信息

产品名称产品编号规格价格数量收藏夹

CEACAM5/6 抗体 (By114)

sc-20059
200 µg/ml
$316.00

CEACAM5/6 (By114): m-IgG Fc BP-HRP 套装

sc-536649
200 µg Ab; 10 µg BP
$354.00

CEACAM5/6 (By114): m-IgGκ BP-HRP 套装

sc-533807
200 µg Ab; 40 µg BP
$354.00

CEACAM5/6 (By114): m-IgG1 BP-HRP 套装

sc-544733
200 µg Ab; 20 µg BP
$354.00

CEACAM5/6 抗体 (By114) FITC

sc-20059 FITC
200 µg/ml
$330.00

CEACAM5/6 抗体 (By114) PE

sc-20059 PE
200 µg/ml
$343.00

If I order one product, when can I receive it to Suwon, Korea.

Asked by: LimJ
Thank you for your question. Please contact our distributors in Korea. https://www.scbt.com/resources/distributors KOREA For ordering or product information contact us at: Essence Medical Inc. 417 Leaders B/D, Yatapdong 342-1 Bundanggu Seongnam Gyeonggi-do Korea Phone: 82-31-707-1544 Fax: 82-31-707-1999 Email: info@essencemedical.com Website: www.essencemedical.com Koram Biotech Corporation 6F, Koram Venture Building 907-1 Daechi-Dong Kang Nam-Ku Seoul 135-080 Korea Phone: 82 (2) 556-0311 Fax: 82 (2) 556-0828 Email: koram@korambiotech.com Website: www.korambiotech.com
Answered by: Ling Chen
Date published: 2024-09-29

How can CEACAM5/6 (By114): sc-20059 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

Asked by: Trav11
In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to phycoerythrin (sc-20059 PE) or fluoroscein (sc-20059 FITC).
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from WB: strongWB: strong, clean band in MCF7 whole cell lysate. -SCBT QC
Date published: 2015-05-20
Rated 4 out of 5 by from Positive results in western blot using humanPositive results in western blot using human CEA transfected 293T and T84 whole cell lysates. -SCBT QC
Date published: 2015-05-12
Rated 5 out of 5 by from Produced exceptional immunoperoxidase membraneProduced exceptional immunoperoxidase membrane and cytoplasmic staining in formalin fixed, paraffin-embedded human appendix tissue. -SCBT QC
Date published: 2015-01-12
Rated 5 out of 5 by from Great FCM data of human peripheral bloodGreat FCM data of human peripheral blood leukocytes. -SCBT QC
Date published: 2014-04-30
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CEACAM5/6 抗体 (By114) is rated 4.8 out of 5 by 4.
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