CEACAM5 Activators
CEACAM5 activators belong to a distinct chemical class of compounds known for their capacity to modulate the activity of the Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5) protein. CEACAM5, also known as CEA (Carcinoembryonic Antigen), is a cell surface glycoprotein that belongs to the CEACAM family. It is primarily expressed in epithelial tissues and is often overexpressed in various cancers, including colorectal, pancreatic, and lung cancers. CEACAM5 plays a role in cell adhesion, cellular signaling, and immune response modulation, and its dysregulation is associated with tumorigenesis and cancer progression.
The activators within this chemical class can function by either enhancing or inhibiting the activity of CEACAM5, depending on their specific mechanisms of action. Researchers are interested in these molecules due to their ability to elucidate the intricate molecular pathways involved in cancer development and progression. Understanding how CEACAM5 activators impact the function of this cell adhesion molecule is essential for unraveling the role of CEACAM5 in cancer biology and its implications in tumor growth and metastasis. This research area contributes to our knowledge of the molecular mechanisms underlying cancer cell behavior and the avenues for targeting CEACAM5.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Butyric acid | 107-92-6 | sc-214640 sc-214640A | 1 kg 10 kg | $64.00 $177.00 | ||
Butyric acid, a short-chain fatty acid, may influence gene expression through histone deacetylase inhibition, potentially affecting CEACAM5 expression in epithelial cells. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, a metabolite of Vitamin A, can regulate gene expression and differentiation in various cell types, possibly inducing CEACAM5 expression in certain contexts. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
Fluorouracil can influence DNA synthesis and repair mechanisms, potentially altering the expression of genes like CEACAM5 in cancer cells. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
β-Estradiol can modulate gene expression through its receptors, potentially influencing the expression of CEACAM5 in hormone-responsive tissues. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $272.00 | 18 | |
Tamoxifen, an estrogen receptor modulator, can affect gene expression in hormone-responsive cells, potentially altering CEACAM5 levels. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Cholecalciferol, through its receptor, can modulate the expression of various genes, possibly including CEACAM5, especially in epithelial cells. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin can induce DNA damage responses, potentially altering gene expression profiles including CEACAM5 in cancer cells. | ||||||