Cdk7 Antibody (G-5): sc-393308
- Cdk7 Antibody (G-5) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1-24 at the N-terminus of Cdk7 of human origin
- recommended for detection of Cdk7 of mouse, rat, human and monkey origin by WB, IP, IF and ELISA
- See Cdk7 (C-4): sc-7344 for Cdk7 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Cdk7 Antibody (G-5) for WB applications. These reagents are now offered in bundles with Cdk7 Antibody (G-5) (see ordering information below).
Cdk7 Antibody (G-5) is a mouse monoclonal IgG1 antibody that detects Cdk7 in mouse, rat, human, and monkey samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Cdk7 plays a pivotal role in the regulation of the cell cycle by functioning as a cyclin-dependent kinase-activating kinase (CAK), which is essential for the activation of other cyclin-dependent kinases, including Cdk2 and Cdc2. Cdk7′s importance lies in its ability to phosphorylate these kinases at specific threonine residues, which is crucial for their full enzymatic activity and, consequently, for the proper progression of the cell cycle. The structure of Cdk7 includes a conserved threonine residue that is vital for its catalytic function; mutations in this residue can lead to a significant reduction in CAK activity, thereby disrupting cell cycle regulation. Anti-Cdk7 antibody (G-5) is an invaluable tool for researchers studying cell cycle dynamics and the intricate signaling pathways that govern cellular proliferation and differentiation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdk7 Antibody (G-5) | sc-393308 | 200 µg/ml | $322.00 | |||
Cdk7 Antibody (G-5): m-IgG Fc BP-HRP Bundle | sc-540897 | 200 µg Ab; 10 µg BP | $361.00 | |||
Cdk7 Antibody (G-5): m-IgG1 BP-HRP Bundle | sc-542449 | 200 µg Ab; 20 µg BP | $361.00 | |||
Cdk7 (G-5) Neutralizing Peptide | sc-393308 P | 100 µg/0.5 ml | $69.00 |