Olfr665 Inhibitors
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Items 11 to 18 of 18 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
trans-Anethole | 4180-23-8 | sc-253727 | 1 ml | $28.00 | 1 | |
Anethole activates Olfr665 by interacting with its ligand-binding domain, inducing a structural change and activating the GPCR signaling pathway for olfactory signal propagation. | ||||||
Ethyl butyrate | 105-54-4 | sc-214986 sc-214986A | 1 kg 4 kg | $100.00 $210.00 | ||
Ethyl butyrate activates Olfr665 by binding to the ligand-binding domain, causing a structural change and activating the GPCR pathway for olfactory signal transmission. | ||||||
Amiloride | 2609-46-3 | sc-337527 | 1 g | $296.00 | 7 | |
Amiloride serves as an indirect inhibitor by blocking epithelial sodium channels (ENaC). It affects the ion homeostasis in olfactory neurons, influencing the resting membrane potential and modulating Olfr665-mediated signal transduction, leading to reduced smell perception. | ||||||
Cinnamic Aldehyde | 104-55-2 | sc-294033 sc-294033A | 100 g 500 g | $104.00 $228.00 | ||
Cinnamic Aldehyde activates Olfr665 by direct interaction with the receptor, binding to the ligand-binding domain, and inducing a conformational change that triggers G protein-mediated signaling. | ||||||
α-Pinene | 80-56-8 | sc-233784 sc-233784A | 5 ml 250 ml | $52.00 $115.00 | 2 | |
Alpha-Pinene activates Olfr665 by binding to its ligand-binding domain, causing a structural change in the receptor, and initiating the GPCR-mediated signaling pathway for olfactory signal transduction. | ||||||
Picrotoxin | 124-87-8 | sc-202765 sc-202765A sc-202765B | 1 g 5 g 25 g | $67.00 $286.00 $1326.00 | 11 | |
Picrotoxin serves as an indirect inhibitor by blocking GABA-A receptors. It modulates inhibitory neurotransmission in olfactory circuits, influencing the balance between excitatory and inhibitory signals related to Olfr665, resulting in altered olfactory perception. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin acts as a direct inhibitor by inhibiting phosphoinositide 3-kinase (PI3K). It disrupts the PI3K-dependent signaling pathway associated with Olfr665, leading to impaired olfactory receptor activation and reduced perception of odorant stimuli. | ||||||
Citral | 5392-40-5 | sc-252620 | 1 kg | $212.00 | ||
Citral activates Olfr665 by binding to specific receptor sites, inducing a conformational change, and initiating a G protein-mediated signal transduction pathway for olfactory perception. | ||||||