RSRC2 Antibody (D-3): sc-515073
- RSRC2 Antibody (D-3) is a mouse monoclonal IgG1 κ RSRC2 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 275-434 mapping at the C-terminus of RSRC2 of human origin
- RSRC2 Antibody (D-3) is recommended for detection of RSRC2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-RSRC2 Antibody (D-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for RSRC2 Antibody (D-3) for WB applications. These reagents are now offered in bundles with RSRC2 Antibody (D-3) (see ordering information below).
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RSRC2 Antibody (D-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects RSRC2 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RSRC2 (D-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. RSRC2, also known as arginine/serine-rich coiled-coil protein 2, consists of 434 amino acids and plays a crucial role as a transcription factor that regulates cell proliferation. RSRC2 expression is ubiquitous, with a predominant localization in the nucleus, where RSRC2 functions as a tumor suppressor in esophageal squamous cell carcinoma (ESCC). RSRC2 inhibits cell proliferation in ESCC cell lines, and RSRC2 downregulation is associated with tumor progression, highlighting RSRC2′s potential as a therapeutic target for esophageal cancer. RSRC2 is expressed in two isoforms due to alternative splicing, which may contribute to RSRC2′s functional diversity in cellular processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
RSRC2 Antibody (D-3) References:
- Amplification and expression of the human cyclin D gene in esophageal cancer. | Jiang, W., et al. 1992. Cancer Res. 52: 2980-3. PMID: 1533816
- A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. | Lim, J., et al. 2006. Cell. 125: 801-14. PMID: 16713569
- A novel gene, RSRC2, inhibits cell proliferation and affects survival in esophageal cancer patients. | Kurehara, H., et al. 2007. Int J Oncol. 30: 421-8. PMID: 17203224
- Descriptive epidemiology of esophageal carcinoma in the Ohio Cancer Registry. | Cummings, LC. and Cooper, GS. 2008. Cancer Detect Prev. 32: 87-92. PMID: 18406068
- Role of histone deacetylase inhibitor in adenovirus-mediated p53 gene therapy in esophageal cancer. | Hoshino, I., et al. 2008. Anticancer Res. 28: 665-71. PMID: 18507005
- Esophageal and gastric cardia cancers on 4238 Chinese patients residing in municipal and rural regions: a histopathological comparison during 24-year period. | Fan, YJ., et al. 2008. World J Surg. 32: 1980-8. PMID: 18566857
- K-ras mutation, HPV infection and smoking or alcohol abuse positively correlate with esophageal squamous carcinoma. | Lyronis, ID., et al. 2008. Pathol Oncol Res. 14: 267-73. PMID: 18592405
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RSRC2 Antibody (D-3) | sc-515073 | 200 µg/ml | $316.00 | |||
RSRC2 Antibody (D-3): m-IgG Fc BP-HRP Bundle | sc-531281 | 200 µg Ab; 10 µg BP | $354.00 | |||
RSRC2 Antibody (D-3): m-IgGκ BP-HRP Bundle | sc-524926 | 200 µg Ab, 40 µg BP | $354.00 | |||
RSRC2 Antibody (D-3) AC | sc-515073 AC | 500 µg/ml, 25% agarose | $416.00 | |||
RSRC2 Antibody (D-3) HRP | sc-515073 HRP | 200 µg/ml | $316.00 | |||
RSRC2 Antibody (D-3) FITC | sc-515073 FITC | 200 µg/ml | $330.00 | |||
RSRC2 Antibody (D-3) PE | sc-515073 PE | 200 µg/ml | $343.00 | |||
RSRC2 Antibody (D-3) Alexa Fluor® 488 | sc-515073 AF488 | 200 µg/ml | $357.00 | |||
RSRC2 Antibody (D-3) Alexa Fluor® 546 | sc-515073 AF546 | 200 µg/ml | $357.00 | |||
RSRC2 Antibody (D-3) Alexa Fluor® 594 | sc-515073 AF594 | 200 µg/ml | $357.00 | |||
RSRC2 Antibody (D-3) Alexa Fluor® 647 | sc-515073 AF647 | 200 µg/ml | $357.00 | |||
RSRC2 Antibody (D-3) Alexa Fluor® 680 | sc-515073 AF680 | 200 µg/ml | $357.00 | |||
RSRC2 Antibody (D-3) Alexa Fluor® 790 | sc-515073 AF790 | 200 µg/ml | $357.00 |