RSRC2 Activators
RSRC2, or Arginine/Serine-Rich Coiled-Coil 2, is a protein encoded by the RSRC2 gene in humans. It is a member of the serine/arginine-rich (SR) family of proteins, which are known for their involvement in RNA splicing, an essential process in gene expression.The primary function of RSRC2, like other SR proteins, is to regulate alternative splicing of pre-mRNA. Alternative splicing is a mechanism that allows a single gene to produce multiple protein variants, significantly expanding the diversity of the proteome. RSRC2 achieves this by interacting with specific sequences in pre-mRNA and influencing the assembly and function of the spliceosome, a complex responsible for removing introns from pre-mRNA.
RSRC2 is characterized by an RS domain, rich in arginine and serine residues, which is typical of SR proteins. This domain is crucial for protein-protein and protein-RNA interactions during the splicing process. RSRC2 also features a coiled-coil domain, which contributes to its structural configuration and its interactions with other proteins.The role of RSRC2 in RNA splicing makes it important for the proper expression and function of many genes. Dysregulation of alternative splicing or mutations in splicing factors like RSRC2 can lead to aberrant splicing patterns, which are implicated in various diseases, including cancer and neurodegenerative disorders.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pladienolide B | 445493-23-2 | sc-391691 sc-391691B sc-391691A sc-391691C sc-391691D sc-391691E | 0.5 mg 10 mg 20 mg 50 mg 100 mg 5 mg | $299.00 $5699.00 $11099.00 $25500.00 $66300.00 $2875.00 | 63 | |
Pladienolide B targets the spliceosome and can influence RNA splicing, potentially impacting RSRC2-related pathways. | ||||||
Spliceostatin A | 391611-36-2 | sc-507481 | 1 mg | $1800.00 | ||
Spliceostatin A, found in a natural product, is a potent inhibitor of the spliceosome, potentially affecting RSRC2 function. | ||||||
Isoginkgetin | 548-19-6 | sc-507430 | 5 mg | $225.00 | ||
Isoginkgetin is a natural biflavonoid compound that inhibits splicing, potentially affecting RSRC2-related processes. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Chloroquine, known for its effects on lysosomal function, can also influence RNA processing and potentially impact RSRC2. | ||||||
Amiloride | 2609-46-3 | sc-337527 | 1 g | $296.00 | 7 | |
Amiloride, primarily a diuretic, has been shown to affect RNA splicing, potentially impacting RSRC2. | ||||||
Kinetin | 525-79-1 | sc-207780 sc-207780A | 1 g 5 g | $38.00 $48.00 | ||
Kinetin, a cytokinin, can influence RNA splicing, potentially affecting RSRC2 function. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Etoposide, a topoisomerase inhibitor, can affect DNA replication and transcription, potentially impacting RNA processing involving RSRC2. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A, a histone deacetylase inhibitor, affects chromatin structure and gene expression, potentially impacting RSRC2. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Mithramycin, an antibiotic with antitumor properties, can affect transcription and potentially RNA splicing processes involving RSRC2. | ||||||