Anti-Id1 Anticorpo B-8é um anticorpo monoclonal produzido em camundongo IgG2a κ Id1 anticorpo, citado em 23 publicações, fornecido em 200 µg/ml
específico para um epítopo mapeado entre os aminoácidos118-159 no C-terminus de Id1 de mouse origem
Anti-Id1 Anticorpo (B-8) é recomendado para a detecção de Id1 de mouse, rat e human origem em WB, IP, IF, IHC(P) e ELISA; reage também com outras espécies, incluindo canine
Anti-Id1 Antibody (B-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
disponível como reagente TransCruz para ensaios de Gel Supershift e uso em ChIP (sc-133104 X, 200 µg/0.1 ml)
Entre em contato conosco e receba GRATUITAMENTE um amostra de 10 µg de Id1 (B-8): sc-133104.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for Id1 Antibody (B-8) for WB and IHC(P) applications. This reagent is now offered in a bundle with Id1 Antibody (B-8) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
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Id1 Antibody (B-8) is a high quality monoclonal Id1 antibody (also designated Inhibitor of DNA binding 1 antibody, ID1 antibody or bHLHb24 antibody) suitable for the detection of the Id1 protein of mouse, rat and human origin. Id1 Antibody (B-8) is available as both the non-conjugated anti-Id1 antibody form, as well as multiple conjugated forms of anti-Id1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Members of the Id family of basic helix-loop-helix (bHLH) proteins include Id1, Id2, Id3 and Id4. They are ubiquitously expressed and dimerize with members of the class A and B HLH proteins. Due to the absence of the basic region, the resulting heterodimers cannot bind DNA. The Id-type proteins thus appear to negatively regulate DNA binding of bHLH proteins. Since Id1 inhibits DNA binding of E12 and Myo D, it apparently functions to inhibit muscle-specific gene expression. Under conditions that facilitate muscle cell differentiation, the Id protein levels fall, allowing E12 and/or E47 to form heterodimers with Myo D and myogenin, which in turn activate myogenic differentiation. It has been shown that expression of each of the Id proteins is strongly dependent on growth factor activation and that reduction of Id mRNA levels by antisense oligonucleotides leads to a delayed reentry of arrested cells into the cell cycle following growth factor stimulation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn