CD34 Antibody (CBR-E8): sc-52478
- CD34 Antibody (CBR-E8) is a rat monoclonal IgM, cited in 4 publications, provided at 200 µg/ml
- raised against recombinant CD34-GST fusion protein of mouse origin
- recommended for detection of CD34 of mouse and rat origin by WB, IP and IF
- See CD34 (B-6): sc-74499 for CD34 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD34 Antibody (CBR-E8). This work is in progress.
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CD34 Antibody (CBR-E8) is a rat monoclonal IgM antibody that recognizes CD34 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). CD34 is a heavily glycosylated, transmembrane glycoprotein that plays a crucial role in the regulation of hematopoietic stem cell adhesion and migration, making anti-CD34 antibody (CBR-E8) essential for studying the hematopoietic system. CD34 is predominantly expressed on the surface of lymphohematopoietic stem and progenitor cells, small-vessel endothelial cells, embryonic fibroblasts, and certain cells in both fetal and adult nervous tissue. CD34 expression is highest in primitive stem cells, gradually diminishing as these cells differentiate into lineage-committed progenitors. CD34 presence on capillary endothelial cells and bone marrow stromal cells further underscores CD34′s importance in vascular biology and tissue homeostasis. The cytoplasmic domain of CD34 contains consensus sites for phosphorylation by activated protein kinase C (PKC), along with serine, threonine, and tyrosine phosphorylation sites, which are critical for mediating intracellular signaling pathways that influence cell behavior. CD34 monoclonal antibody (CBR-E8) serves as an invaluable tool for researchers studying stem cell biology, vascular development, and mechanisms underlying cell adhesion and migration.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD34 Antibody (CBR-E8) | sc-52478 | 200 µg/ml | $322.00 |