The category of compounds identified as Vmn2r12 Inhibitors consists of chemicals that, while not directly targeting Vmn2r12, exert their influence on various signaling pathways and cellular processes that could, in turn, modulate the activity or expression of Vmn2r12. These compounds operate through diverse mechanisms, such as antagonism of specific receptors, inhibition of kinase activity, modulation of calcium signaling, and alteration of cytoskeletal dynamics. Through these mechanisms, they have the capacity to indirectly impact the signal transduction pathways and cellular contexts in which Vmn2r12 functions, thereby offering a strategic approach to studying and potentially modulating the activity of this protein.
The selection of these compounds reflects a nuanced understanding of cellular signaling as a highly interconnected network, where changes in one part of the system can have widespread effects on other components. By targeting various nodes within this network-such as GPCRs, kinases, and calcium signaling pathways-the listed chemicals can alter the cellular milieu and the flow of biochemical signals within the cell. This, in turn, can influence the activity of Vmn2r12, even in the absence of direct interaction with the protein. Such an approach underscores the complexity of cellular signaling and the potential for indirect strategies to elucidate the functions of specific proteins within this web of interactions. Through the modulation of signaling pathways that Vmn2r12 is either directly or indirectly involved in, these compounds provide valuable tools for probing the biological roles of Vmn2r12 and for exploring the intricate regulatory mechanisms that govern cellular response mechanisms.
VEJA TAMBÉM
Items 11 to 17 of 17 total
Mostrar:
| Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
|---|---|---|---|---|---|---|
LY 364947 | 396129-53-6 | sc-203122 sc-203122A | 5 mg 10 mg | $107.00 $156.00 | 4 | |
Um inibidor seletivo do recetor de TGF-beta tipo I, potencialmente influenciando as vias de sinalização relevantes para o Vmn2r12. | ||||||
Chelerythrine | 34316-15-9 | sc-507380 | 100 mg | $540.00 | ||
Inibe a PKC, afectando potencialmente as vias de sinalização GPCR que podem ser relevantes para a função do Vmn2r12. | ||||||
Pimozide | 2062-78-4 | sc-203662 | 100 mg | $104.00 | 3 | |
A pimozida é um fármaco antipsicótico com elevada afinidade pelos receptores de serotonina. Poderia inibir o Vmn2r121 bloqueando estes receptores e interrompendo as vias de sinalização mediadas pela serotonina de que o Vmn2r121 poderia fazer parte. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $182.00 | 25 | |
Inibe a proteína quinase II dependente de Ca2+/calmodulina (CaMKII), influenciando potencialmente as vias de sinalização do cálcio relevantes para o Vmn2r12. | ||||||
Spiperone | 749-02-0 | sc-471047 | 250 mg | $130.00 | ||
A espiperona é um potente antagonista dos receptores da dopamina e da serotonina. Ao inibir estes receptores, poderia perturbar as vias de sinalização que envolvem a Vmn2r121, conduzindo a uma diminuição da atividade funcional da proteína. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
Inibe a MEK1/2, afectando potencialmente as vias de sinalização MAPK/ERK em que o Vmn2r12 pode estar envolvido. | ||||||
Tyrphostin AG 1478 | 175178-82-2 | sc-200613 sc-200613A | 5 mg 25 mg | $96.00 $421.00 | 16 | |
Inibe a tirosina quinase EGFR, potencialmente modulando as vias de sinalização que se cruzam com a atividade do Vmn2r12. | ||||||