Date published: 2026-6-4

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POLR2B Antibodies

Santa Cruz Biotechnology delivers a wide array of POLR2B monoclonal antibodies for investigating RNA polymerase II in transcription regulation. POLR2B monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). POLR2B, the second largest subunit of RNA polymerase II, plays a crucial role in synthesizing messenger RNA (mRNA) from DNA templates, making it essential for gene expression and cellular function. RNA polymerase II's proper functioning is vital for various biological processes, including cell growth, differentiation, and response to environmental signals. Dysregulation of POLR2B has been implicated in several diseases, highlighting its significance as a target for therapeutic intervention. Researchers can explore POLR2B's role in normal cellular processes and disease states through multiple experimental approaches. Understanding POLR2B function contributes to knowledge about transcriptional control mechanisms and potential therapeutic strategies. POLR2B research advances our understanding of fundamental cellular processes and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of transcriptional regulation and its impact on human health.

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POLR2B Antibodies

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POLR2B Antibody (E-12)

sc-166803mouse IgG2a κ184-384 (h)WB, IP, IF, ELISAm, r, h
9
(2)

POLR2B CRISPR Activation Products

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RPB2 CRISPR Activation Plasmid (h)

sc-402591-ACThGene ActivationPuro, Blast, Hygro0
(0)

POLR2B siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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POLR2B siRNA (h)

sc-62962hGene SilencingN/A0
(0)

POLR2B shRNA Plasmid (h)

sc-62962-SHhGene SilencingPuromycin0
(0)

POLR2B shRNA (h) Lentiviral Particles

sc-62962-VhGene SilencingPuromycin0
(0)

POLR2B siRNA (m)

sc-62963mGene SilencingN/A0
(0)

POLR2B shRNA Plasmid (m)

sc-62963-SHmGene SilencingPuromycin0
(0)

POLR2B shRNA (m) Lentiviral Particles

sc-62963-VmGene SilencingPuromycin0
(0)