Date published: 2026-7-19

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Granzyme Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Granzyme Antibodies for research in understanding the mechanisms of immune response and apoptosis. Granzyme Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Granzyme proteins play a crucial role in the immune system, particularly in the cytotoxic activity of T cells and natural killer cells. Serine proteases induce apoptosis in target cells, making Granzyme essential for the elimination of infected or malignant cells. Understanding the function and regulation of Granzyme proteins advances the development of therapeutic strategies against cancer and autoimmune diseases. Researchers worldwide utilize Granzyme monoclonal antibodies to explore cellular mechanisms and pathways involved in immune responses. Current investigations focus on how Granzyme proteins interact with different cellular components and their impact on various disease states. The application of Santa Cruz Biotechnology monoclonal antibodies continues to drive discoveries in immunology and cell biology research, supporting scientists in their quest to understand complex immune system mechanisms.

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Granzyme Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

granzyme A Antibody (3G8.5)

sc-33692mouse IgG2b κFL (m)WB, IP, FCM, ELISAm
9
(3)

granzyme A Antibody (CB9)

sc-56115mouse IgG1 κFL (h)IP, IF, FCM, ELISAh
1
(1)

granzyme B Antibody (2C5)

sc-8022mouse IgG2a κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
56
(17)

granzyme B Antibody (GB7)

sc-56119mouse IgG2a1-247 (h)WB, IP, IF, IHC(P)h
2
(2)

granzyme B Antibody (GRB7)

sc-73620mouse IgG2a1-247 (h)WB, IP, IF, IHC(P)h
2
(3)

granzyme K Antibody (GM6C3)

sc-56125mouse IgG2b κ(h)FCMh
25
(2)

granzyme M Antibody (A-10)

sc-376799mouse IgG1 κ71-140 (h)WB, IP, IF, ELISAm, r, h
1
(2)

granzyme M Antibody (C-10)

sc-393375mouse IgG1 κ82-129 (h)WB, IP, IF, ELISAm, r, h

new

(1)

granzyme M Antibody (C-12)

sc-393155mouse IgG2b κ89-126 (h)WB, IP, IF, ELISAh

new

(1)

Granzyme siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

granzyme A siRNA (h)

sc-37431hGene SilencingN/A0
(0)

granzyme A shRNA Plasmid (h)

sc-37431-SHhGene SilencingPuromycin0
(0)

granzyme A shRNA (h) Lentiviral Particles

sc-37431-VhGene SilencingPuromycin0
(0)

granzyme A siRNA (m)

sc-37432mGene SilencingN/A0
(0)

granzyme A shRNA Plasmid (m)

sc-37432-SHmGene SilencingPuromycin0
(0)

granzyme A shRNA (m) Lentiviral Particles

sc-37432-VmGene SilencingPuromycin0
(0)

granzyme B siRNA (h)

sc-35507hGene SilencingN/A0
(0)

granzyme B shRNA Plasmid (h)

sc-35507-SHhGene SilencingPuromycin0
(0)

granzyme B shRNA (h) Lentiviral Particles

sc-35507-VhGene SilencingPuromycin0
(0)

granzyme B siRNA (m)

sc-35508mGene SilencingN/A
1
(0)

granzyme B shRNA Plasmid (m)

sc-35508-SHmGene SilencingPuromycin
1
(0)

granzyme B shRNA (m) Lentiviral Particles

sc-35508-VmGene SilencingPuromycin
1
(0)

granzyme C siRNA (m)

sc-105411mGene SilencingN/A0
(0)

granzyme C shRNA Plasmid (m)

sc-105411-SHmGene SilencingPuromycin0
(0)

granzyme C shRNA (m) Lentiviral Particles

sc-105411-VmGene SilencingPuromycin0
(0)

granzyme D siRNA (m)

sc-105412mGene SilencingN/A0
(0)

granzyme D shRNA Plasmid (m)

sc-105412-SHmGene SilencingPuromycin0
(0)

granzyme D shRNA (m) Lentiviral Particles

sc-105412-VmGene SilencingPuromycin0
(0)

granzyme F siRNA (m)

sc-105413mGene SilencingN/A0
(0)

granzyme F shRNA Plasmid (m)

sc-105413-SHmGene SilencingPuromycin0
(0)

granzyme F shRNA (m) Lentiviral Particles

sc-105413-VmGene SilencingPuromycin0
(0)

granzyme G siRNA (m)

sc-105414mGene SilencingN/A0
(0)

granzyme G shRNA Plasmid (m)

sc-105414-SHmGene SilencingPuromycin0
(0)

granzyme G shRNA (m) Lentiviral Particles

sc-105414-VmGene SilencingPuromycin0
(0)

granzyme H siRNA (h)

sc-60757hGene SilencingN/A0
(0)

granzyme H shRNA Plasmid (h)

sc-60757-SHhGene SilencingPuromycin0
(0)

granzyme H shRNA (h) Lentiviral Particles

sc-60757-VhGene SilencingPuromycin0
(0)

granzyme K siRNA (h)

sc-60759hGene SilencingN/A
1
(0)

granzyme K shRNA Plasmid (h)

sc-60759-SHhGene SilencingPuromycin
1
(0)

granzyme K shRNA (h) Lentiviral Particles

sc-60759-VhGene SilencingPuromycin
1
(0)

granzyme K siRNA (m)

sc-60760mGene SilencingN/A0
(0)

granzyme K shRNA Plasmid (m)

sc-60760-SHmGene SilencingPuromycin0
(0)

granzyme K shRNA (m) Lentiviral Particles

sc-60760-VmGene SilencingPuromycin0
(0)

granzyme M siRNA (h)

sc-60761hGene SilencingN/A0
(0)

granzyme M shRNA Plasmid (h)

sc-60761-SHhGene SilencingPuromycin0
(0)

granzyme M shRNA (h) Lentiviral Particles

sc-60761-VhGene SilencingPuromycin0
(0)

granzyme M siRNA (m)

sc-60762mGene SilencingN/A0
(0)

granzyme M shRNA Plasmid (m)

sc-60762-SHmGene SilencingPuromycin0
(0)

granzyme M shRNA (m) Lentiviral Particles

sc-60762-VmGene SilencingPuromycin0
(0)

granzyme N siRNA (m)

sc-105415mGene SilencingN/A0
(0)

granzyme N shRNA Plasmid (m)

sc-105415-SHmGene SilencingPuromycin0
(0)

granzyme N shRNA (m) Lentiviral Particles

sc-105415-VmGene SilencingPuromycin0
(0)

Granzyme CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

granzyme A CRISPR/Cas9 KO Plasmid (h)

sc-403958Gene Knockouth0
(0)

granzyme A HDR Plasmid (h)

sc-403958-HDRHomology Directed Repairh0
(0)

granzyme B CRISPR/Cas9 KO Plasmid (h)

sc-401469Gene Knockouth0
(0)

granzyme B HDR Plasmid (h)

sc-401469-HDRHomology Directed Repairh0
(0)

granzyme A CRISPR/Cas9 KO Plasmid (bovine)

sc-437323Gene Knockoutbovine0
(0)

granzyme B CRISPR/Cas9 KO Plasmid (m)

sc-420745Gene Knockoutm0
(0)

granzyme B HDR Plasmid (m)

sc-420745-HDRHomology Directed Repairm0
(0)

granzyme K CRISPR/Cas9 KO Plasmid (h)

sc-407038Gene Knockouth0
(0)

Granzyme CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

granzyme A Double Nickase Plasmid (h)

sc-403958-NICGene Knockouth0
(0)

granzyme A Double Nickase Plasmid (h2)

sc-403958-NIC-2Gene Knockouth0
(0)

granzyme B Double Nickase Plasmid (h)

sc-401469-NICGene Knockouth0
(0)

granzyme B Double Nickase Plasmid (h2)

sc-401469-NIC-2Gene Knockouth0
(0)

granzyme B Double Nickase Plasmid (m)

sc-420745-NICGene Knockoutm0
(0)

granzyme B Double Nickase Plasmid (m2)

sc-420745-NIC-2Gene Knockoutm0
(0)

Granzyme CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

granzyme A CRISPR Activation Plasmid (h)

sc-403958-ACTGene Activationh0
(0)

granzyme B CRISPR Activation Plasmid (h)

sc-401469-ACTGene Activationh0
(0)

granzyme B CRISPR Activation Plasmid (h2)

sc-401469-ACT-2Gene Activationh0
(0)

granzyme B CRISPR Activation Plasmid (m)

sc-420745-ACTGene Activationm0
(0)

granzyme B CRISPR Activation Plasmid (m2)

sc-420745-ACT-2Gene Activationm0
(0)