Date published: 2026-6-3

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CYP11B Antibodies

Santa Cruz Biotechnology provides a broad selection of CYP11B monoclonal antibodies for research in steroidogenesis and adrenal function. CYP11B Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CYP11B, or cytochrome P450 11B, plays a crucial role in the biosynthesis of steroid hormones, particularly in the conversion of progesterone to cortisol and aldosterone. CYP11B is essential for maintaining electrolyte balance and regulating blood pressure, making it a significant focus in studies related to adrenal disorders and hypertension. Understanding CYP11B function is vital for advancing therapeutic strategies in endocrine diseases. Research into CYP11B has revealed its significance in maintaining hormonal homeostasis and its potential as a therapeutic target. Investigating CYP11B expression patterns helps scientists better understand the mechanisms behind various endocrine disorders. Current studies focusing on CYP11B continue to uncover new insights into steroid hormone regulation and metabolism. Santa Cruz Biotechnology monoclonal antibodies for CYP11B support researchers worldwide in advancing our understanding of endocrine system function and disease treatment.

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CYP11B Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CYP11B1 Antibody (A-11)

sc-377401mouse IgG2a κ367-397 (r)WB, IP, IF, IHC(P), ELISAm, r
3
(2)

CYP11B1 Antibody (H-11)

sc-374096mouse IgG2a κ204-503 (deletion 401-466) (h)WB, IP, IF, IHC(P), ELISAh
3
(3)

CYP11B1 Antibody (B-11)

sc-377248mouse IgG1 κ367-397 (r)WB, IP, IF, ELISAm, r
1
(1)

CYP11B CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CYP11B2 CRISPR/Cas9 KO Plasmid (h)

sc-405281hGene KnockoutGFP0
(0)

CYP11B2 HDR Plasmid (h)

sc-405281-HDRhHomology Directed RepairPuromycin0
(0)

CYP11B2 Double Nickase Plasmid (h)

sc-405281-NIChGene KnockoutPuromycin0
(0)

CYP11B2 Double Nickase Plasmid (h2)

sc-405281-NIC-2hGene KnockoutPuromycin0
(0)

CYP11B2 CRISPR/Cas9 KO Plasmid (m)

sc-419894mGene KnockoutGFP0
(0)

CYP11B CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CYP11B2 CRISPR Activation Plasmid (h)

sc-405281-ACThGene ActivationPuro, Blast, Hygro0
(0)

CYP11B siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CYP11B2 siRNA (h)

sc-44861hGene SilencingN/A
1
(0)

CYP11B2 shRNA Plasmid (h)

sc-44861-SHhGene SilencingPuromycin
1
(0)

CYP11B2 shRNA (h) Lentiviral Particles

sc-44861-VhGene SilencingPuromycin
1
(0)

CYP11B2 siRNA (m)

sc-44862mGene SilencingN/A0
(0)

CYP11B2 shRNA Plasmid (m)

sc-44862-SHmGene SilencingPuromycin0
(0)

CYP11B2 shRNA (m) Lentiviral Particles

sc-44862-VmGene SilencingPuromycin0
(0)