The protein known as Maestro Heat Like Repeat Family Member 8 (MROH8) is a member of the MROH family, characterized by the presence of maestro (MRO) heat-like repeats. These repeats are protein-protein interaction motifs that are thought to be involved in complex cellular functions, although the specific roles of many MROH family members, including MROH8, are not fully elucidated.MROH8 is encoded by a gene of the same name and is believed to be evolutionarily conserved, suggesting that it plays a fundamental role in cellular biology. The conservation across different species often indicates involvement in essential processes such as development, cellular signaling, or homeostasis. While the exact function of MROH8 is still being studied, proteins with heat-like repeats are generally implicated in the regulation of protein folding, stability, and assembly of multi-protein complexes.
Given its structural features, MROH8 may be involved in mediating interactions with other proteins within the cell, potentially participating in signaling pathways or contributing to the structural organization within the cell. The 'heat-like repeats' suggest a role in processes that are sensitive to cellular stress or temperature changes, which could affect protein conformation and function.Research into MROH8 typically involves various molecular and cellular biology techniques, including gene expression analysis, protein interaction studies, and functional assays to determine its role in cells or organisms.
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| Nome do Produto | CAS # | Numero de Catalogo | Quantidade | Preco | Uso e aplicacao | NOTAS |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Um inibidor da fosfoinositídeo 3-quinases (PI3K), com impacto no crescimento e sobrevivência das células. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
É também um inibidor da PI3K, afectando a proliferação celular e a apoptose. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inibe o mTOR, influenciando o crescimento celular e a síntese proteica. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Um inibidor da proteína quinase de largo espetro, que afecta várias vias de sinalização. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Um inibidor da p38 MAPK, com impacto nas respostas inflamatórias e nas vias de stress. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inibe a MEK1, afectando o crescimento celular e a apoptose. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Um inibidor da JNK, envolvido nas respostas ao stress e na apoptose. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Um inibidor do proteassoma, que afecta as vias de degradação das proteínas. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Inibe a Ca2+ ATPase do retículo sarcoplasmático/endoplasmático (SERCA), afectando a homeostase do cálcio. | ||||||
Z-VAD-FMK | 187389-52-2 | sc-3067 | 500 µg | $74.00 | 256 | |
Um inibidor da caspase de largo espetro, que afecta as vias da apoptose. | ||||||