ZSWIM8 Antibody (G-5): sc-514204
- ZSWIM8 Antibody (G-5) is a mouse monoclonal IgG1 κ ZSWIM8 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1674-1700 near the C-terminus of ZSWIM8 of human origin
- ZSWIM8 Antibody (G-5) is recommended for detection of ZSWIM8 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ZSWIM8 Antibody (G-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ZSWIM8 Antibody (G-5) for WB applications. These reagents are now offered in bundles with ZSWIM8 Antibody (G-5) (see ordering information below).
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ZSWIM8 Antibody (G-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZSWIM8 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZSWIM8 (G-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZSWIM8 protein, consisting of 1,837 amino acids, features a SWIM-type zinc finger motif, which is crucial for protein-protein interactions and transcriptional regulation. ZSWIM8 protein undergoes post-translational modification through phosphorylation at serine residues 567, 1040, and 1042, which can influence activity and interactions with other cellular proteins. ZSWIM8 exists as five alternatively spliced isoforms, and ZSWIM8 gene is located on human chromosome 10, a region that harbors over 800 genes and is associated with various genetic disorders, including Cowden syndrome and Cockayne syndrome. ZSWIM8 research is significant not only for understanding biological functions but also for potential implications in cancer research and therapeutic development, as ZSWIM8 may interact with key regulatory proteins involved in cell cycle control and apoptosis.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZSWIM8 Antibody (G-5) References:
- Molecular cell biology of Charcot-Marie-Tooth disease. | Berger, P., et al. 2002. Neurogenetics. 4: 1-15. PMID: 12030326
- Localization of the nucleotide excision repair gene ERCC6 to human chromosome 10q11-q21. | Troelstra, C., et al. 1992. Genomics. 12: 745-9. PMID: 1349298
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. | Olsen, JV., et al. 2006. Cell. 127: 635-48. PMID: 17081983
- Cowden syndrome-affected patients with PTEN promoter mutations demonstrate abnormal protein translation. | Teresi, RE., et al. 2007. Am J Hum Genet. 81: 756-67. PMID: 17847000
- First report of ovarian dysgerminoma in Cowden syndrome with germline PTEN mutation and PTEN-related 10q loss of tumor heterozygosity. | Cho, MY., et al. 2008. Am J Surg Pathol. 32: 1258-64. PMID: 18594467
- PTEN: a new guardian of the genome. | Yin, Y. and Shen, WH. 2008. Oncogene. 27: 5443-53. PMID: 18794879
- Mutation update for the CSB/ERCC6 and CSA/ERCC8 genes involved in Cockayne syndrome. | Laugel, V., et al. 2010. Hum Mutat. 31: 113-26. PMID: 19894250
- Initial characterization of the human central proteome. | Burkard, TR., et al. 2011. BMC Syst Biol. 5: 17. PMID: 21269460
- Jackson-Weiss and Crouzon syndromes are allelic with mutations in fibroblast growth factor receptor 2. | Jabs, EW., et al. 1994. Nat Genet. 8: 275-9. PMID: 7874170
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZSWIM8 Antibody (G-5) | sc-514204 | 200 µg/ml | $316.00 | |||
ZSWIM8 Antibody (G-5): m-IgG Fc BP-HRP Bundle | sc-531064 | 200 µg Ab; 10 µg BP | $354.00 | |||
ZSWIM8 Antibody (G-5): m-IgGκ BP-HRP Bundle | sc-524647 | 200 µg Ab, 40 µg BP | $354.00 | |||
ZSWIM8 Antibody (G-5): m-IgG1 BP-HRP Bundle | sc-544381 | 200 µg Ab; 20 µg BP | $354.00 | |||
ZSWIM8 Antibody (G-5) AC | sc-514204 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ZSWIM8 Antibody (G-5) HRP | sc-514204 HRP | 200 µg/ml | $316.00 | |||
ZSWIM8 Antibody (G-5) FITC | sc-514204 FITC | 200 µg/ml | $330.00 | |||
ZSWIM8 Antibody (G-5) PE | sc-514204 PE | 200 µg/ml | $343.00 | |||
ZSWIM8 Antibody (G-5) Alexa Fluor® 488 | sc-514204 AF488 | 200 µg/ml | $357.00 | |||
ZSWIM8 Antibody (G-5) Alexa Fluor® 546 | sc-514204 AF546 | 200 µg/ml | $357.00 | |||
ZSWIM8 Antibody (G-5) Alexa Fluor® 594 | sc-514204 AF594 | 200 µg/ml | $357.00 | |||
ZSWIM8 Antibody (G-5) Alexa Fluor® 647 | sc-514204 AF647 | 200 µg/ml | $357.00 | |||
ZSWIM8 Antibody (G-5) Alexa Fluor® 680 | sc-514204 AF680 | 200 µg/ml | $357.00 | |||
ZSWIM8 Antibody (G-5) Alexa Fluor® 790 | sc-514204 AF790 | 200 µg/ml | $357.00 | |||
ZSWIM8 (G-5) Neutralizing Peptide | sc-514204 P | 100 µg/0.5 ml | $68.00 |