ZNRD1 Antibody (D-10): sc-393406
- ZNRD1 Antibody (D-10) is a mouse monoclonal IgG2b κ ZNRD1 antibody, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 71-126 mapping at the C-terminus of ZNRD1 of human origin
- ZNRD1 Antibody (D-10) is recommended for detection of ZNRD1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ZNRD1 Antibody (D-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ZNRD1 Antibody (D-10) for WB applications. These reagents are now offered in bundles with ZNRD1 Antibody (D-10) (see ordering information below).
QUICK LINKS
SEE ALSO...
ZNRD1 Antibody (D-10) is a mouse monoclonal IgG2b kappa light chain antibody that detects ZNRD1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZNRD1 (D-10) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZNRD1 protein, also known as zinc ribbon domain containing 1, TEX6, Rpa12, or hZR14, is a 126 amino acid protein primarily localized in the nucleolus, where ZNRD1 plays a crucial role in synthesizing ribosomal RNA (rRNA) precursors as part of the multi-protein RNA polymerase I complex. This nucleolar localization is significant for ribosome biogenesis, which is vital for protein synthesis in all living cells. ZNRD1 gene is located on human chromosome 6, a region associated with various diseases, including early onset intestinal cancer, Parkinson′s disease, and bipolar disorder, highlighting ZNRD1′s importance in cellular function and potential implications in cancer susceptibility and other genetic disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZNRD1 Antibody (D-10) References:
- A new zinc ribbon gene (ZNRD1) is cloned from the human MHC class I region. | Fan, W., et al. 2000. Genomics. 63: 139-41. PMID: 10662553
- Transcriptional analysis of the 69-kb sequence centromeric to HLA-J: a dense and complex structure of five genes. | Coriton, O., et al. 2000. Mamm Genome. 11: 1127-31. PMID: 11130983
- DARPP-32 mediates multidrug resistance of gastric cancer through regulation of P-gp and ZNRD1. | Hong, L., et al. 2007. Cancer Invest. 25: 699-705. PMID: 18058465
- ZNRD1 might mediate UV irradiation related DNA damage and repair in human esophageal cancer cells by regulation of ERCC1. | Guo, W., et al. 2008. Dis Esophagus. 21: 730-6. PMID: 18564169
- Expression and prognostic value of ZNRD1 in esophageal squamous cell carcinoma. | Zhao, Y., et al. 2009. Dig Dis Sci. 54: 586-92. PMID: 18594968
- HIV-1 disease-influencing effects associated with ZNRD1, HCP5 and HLA-C alleles are attributable mainly to either HLA-A10 or HLA-B*57 alleles. | Catano, G., et al. 2008. PLoS One. 3: e3636. PMID: 18982067
- Systematic sequencing of the human HLA-A/HLA-F region: establishment of a cosmid contig and identification of a new gene cluster within 37 kb of sequence. | Lepourcelet, M., et al. 1996. Genomics. 37: 316-26. PMID: 8938444
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNRD1 Antibody (D-10) | sc-393406 | 200 µg/ml | $322.00 | |||
ZNRD1 Antibody (D-10): m-IgG Fc BP-HRP Bundle | sc-530447 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZNRD1 Antibody (D-10): m-IgGκ BP-HRP Bundle | sc-523934 | 200 µg Ab, 40 µg BP | $361.00 | |||
ZNRD1 Antibody (D-10) AC | sc-393406 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ZNRD1 Antibody (D-10) HRP | sc-393406 HRP | 200 µg/ml | $322.00 | |||
ZNRD1 Antibody (D-10) FITC | sc-393406 FITC | 200 µg/ml | $336.00 | |||
ZNRD1 Antibody (D-10) PE | sc-393406 PE | 200 µg/ml | $349.00 | |||
ZNRD1 Antibody (D-10) Alexa Fluor® 488 | sc-393406 AF488 | 200 µg/ml | $364.00 | |||
ZNRD1 Antibody (D-10) Alexa Fluor® 546 | sc-393406 AF546 | 200 µg/ml | $364.00 | |||
ZNRD1 Antibody (D-10) Alexa Fluor® 594 | sc-393406 AF594 | 200 µg/ml | $364.00 | |||
ZNRD1 Antibody (D-10) Alexa Fluor® 647 | sc-393406 AF647 | 200 µg/ml | $364.00 | |||
ZNRD1 Antibody (D-10) Alexa Fluor® 680 | sc-393406 AF680 | 200 µg/ml | $364.00 | |||
ZNRD1 Antibody (D-10) Alexa Fluor® 790 | sc-393406 AF790 | 200 µg/ml | $364.00 |