ZNF704 Antibody (B-4): sc-514109
- ZNF704 Antibody (B-4) is a mouse monoclonal IgG1 κ ZNF704 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 346-370 near the C-terminus of ZNF704 of human origin
- ZNF704 Antibody (B-4) is recommended for detection of ZNF704 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ZNF704 Antibody (B-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-514109 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ZNF704 Antibody (B-4) for WB applications. These reagents are now offered in bundles with ZNF704 Antibody (B-4) (see ordering information below).
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ZNF704 Antibody (B-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZNF704 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZNF704 (B-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZNF704, also known as Zinc finger protein 704, is a crucial nuclear protein consisting of 412 amino acids and features a single C2H2-type zinc finger domain. ZNF704 plays a significant role in transcriptional regulation, as ZNF704 is involved in recruiting histone-modifying proteins through interaction with KAP1, which is essential for chromatin remodeling and gene expression modulation. The gene encoding ZNF704 is located on human chromosome 8, a region that spans nearly 146 million bases and encodes approximately 800 genes, with implications in various genetic disorders such as Pfeiffer syndrome, congenital hypothyroidism, and Waardenburg syndrome. ZNF704′s ability to influence transcriptional activity underscores its importance in cellular processes and potential implications in developmental biology and disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZNF704 Antibody (B-4) References:
- Chromosomes 8 and 10 workshop. | Wildenauer, DB. and Schwab, SG. 1999. Am J Med Genet. 88: 239-43. PMID: 10374738
- Zinc finger proteins: new insights into structural and functional diversity. | Laity, JH., et al. 2001. Curr Opin Struct Biol. 11: 39-46. PMID: 11179890
- The SCAN domain family of zinc finger transcription factors. | Edelstein, LC. and Collins, T. 2005. Gene. 359: 1-17. PMID: 16139965
- Sticky fingers: zinc-fingers as protein-recognition motifs. | Gamsjaeger, R., et al. 2007. Trends Biochem Sci. 32: 63-70. PMID: 17210253
- Context-dependent DNA recognition code for C2H2 zinc-finger transcription factors. | Liu, J. and Stormo, GD. 2008. Bioinformatics. 24: 1850-7. PMID: 18586699
- Multiple genes encoding zinc finger domains are expressed in human T cells. | Thiesen, HJ. 1990. New Biol. 2: 363-74. PMID: 2288909
- Finger proteins and DNA-specific recognition: distinct patterns of conserved amino acids suggest different evolutionary modes. | Payre, F. and Vincent, A. 1988. FEBS Lett. 234: 245-50. PMID: 3292287
- Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. | Rosenfeld, R. and Margalit, H. 1993. J Biomol Struct Dyn. 11: 557-70. PMID: 8129873
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF704 Antibody (B-4) | sc-514109 | 200 µg/ml | $316.00 | |||
ZNF704 Antibody (B-4): m-IgG Fc BP-HRP Bundle | sc-531032 | 200 µg Ab; 10 µg BP | $354.00 | |||
ZNF704 Antibody (B-4): m-IgGκ BP-HRP Bundle | sc-524609 | 200 µg Ab, 40 µg BP | $354.00 | |||
ZNF704 Antibody (B-4): m-IgG1 BP-HRP Bundle | sc-544368 | 200 µg Ab; 20 µg BP | $354.00 | |||
ZNF704 Antibody (B-4) X | sc-514109 X | 200 µg/0.1 ml | $316.00 | |||
ZNF704 Antibody (B-4) AC | sc-514109 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ZNF704 Antibody (B-4) HRP | sc-514109 HRP | 200 µg/ml | $316.00 | |||
ZNF704 Antibody (B-4) FITC | sc-514109 FITC | 200 µg/ml | $330.00 | |||
ZNF704 Antibody (B-4) PE | sc-514109 PE | 200 µg/ml | $343.00 | |||
ZNF704 Antibody (B-4) Alexa Fluor® 488 | sc-514109 AF488 | 200 µg/ml | $357.00 | |||
ZNF704 Antibody (B-4) Alexa Fluor® 546 | sc-514109 AF546 | 200 µg/ml | $357.00 | |||
ZNF704 Antibody (B-4) Alexa Fluor® 594 | sc-514109 AF594 | 200 µg/ml | $357.00 | |||
ZNF704 Antibody (B-4) Alexa Fluor® 647 | sc-514109 AF647 | 200 µg/ml | $357.00 | |||
ZNF704 Antibody (B-4) Alexa Fluor® 680 | sc-514109 AF680 | 200 µg/ml | $357.00 | |||
ZNF704 Antibody (B-4) Alexa Fluor® 790 | sc-514109 AF790 | 200 µg/ml | $357.00 | |||
ZNF704 (B-4) Neutralizing Peptide | sc-514109 P | 100 µg/0.5 ml | $68.00 |