ZNF703 Antibody (E-6): sc-271896
- ZNF703 Antibody (E-6) is a mouse monoclonal IgG1 κ ZNF703 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 21-43 near the N-terminus of ZNF703 of human origin
- ZNF703 Antibody (E-6) is recommended for detection of ZNF703 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ZNF703 Antibody (E-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-271896 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ZNF703 Antibody (E-6) for WB and IHC(P) applications. These reagents are now offered in bundles with ZNF703 Antibody (E-6) (see ordering information below).
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ZNF703 Antibody (E-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZNF703 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-ZNF703 antibody (E-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZNF703 (E-6) antibody targets a 590 amino acid nuclear protein, characterized by a single C2H2-type zinc finger domain, which is crucial for transcriptional regulation. ZNF703 (E-6) monoclonal antibody recognizes a protein involved in modulating gene expression, making ZNF703 essential for various cellular processes, including development and differentiation. ZNF703 has been implicated in several diseases, including schizophrenia and certain types of cancer, due to regulatory functions. The gene encoding ZNF703 is located on human chromosome 8, a region associated with numerous genetic disorders and malignancies, highlighting the importance of understanding ZNF703 function and interactions. Multiple isoforms of ZNF703 arise from alternative splicing, which may contribute to diverse roles in cellular signaling pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZNF703 Antibody (E-6) References:
- Chromosomes 8 and 10 workshop. | Wildenauer, DB. and Schwab, SG. 1999. Am J Med Genet. 88: 239-43. PMID: 10374738
- Preferential expression of an intact WRN gene in Werner syndrome cell lines in which a normal chromosome 8 has been introduced. | Kashino, G., et al. 2001. Biochem Biophys Res Commun. 289: 111-5. PMID: 11708785
- Cytogenetic mapping of a novel locus for type II Waardenburg syndrome. | Selicorni, A., et al. 2002. Hum Genet. 110: 64-7. PMID: 11810298
- Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. | McQueen, MB., et al. 2005. Am J Hum Genet. 77: 582-95. PMID: 16175504
- High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation. | Pole, JC., et al. 2006. Oncogene. 25: 5693-706. PMID: 16636668
- Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer. | Agrelo, R., et al. 2006. Proc Natl Acad Sci U S A. 103: 8822-7. PMID: 16723399
- Nlz1/Znf703 acts as a repressor of transcription. | Nakamura, M., et al. 2008. BMC Dev Biol. 8: 108. PMID: 19014486
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF703 Antibody (E-6) | sc-271896 | 200 µg/ml | $322.00 | |||
ZNF703 Antibody (E-6): m-IgG Fc BP-HRP Bundle | sc-527304 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZNF703 Antibody (E-6): m-IgG1 BP-HRP Bundle | sc-532677 | 200 µg Ab; 20 µg BP | $361.00 | |||
ZNF703 Antibody (E-6) X | sc-271896 X | 200 µg/0.1 ml | $322.00 | |||
ZNF703 Antibody (E-6) AC | sc-271896 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ZNF703 Antibody (E-6) HRP | sc-271896 HRP | 200 µg/ml | $322.00 | |||
ZNF703 Antibody (E-6) FITC | sc-271896 FITC | 200 µg/ml | $336.00 | |||
ZNF703 Antibody (E-6) PE | sc-271896 PE | 200 µg/ml | $349.00 | |||
ZNF703 Antibody (E-6) Alexa Fluor® 488 | sc-271896 AF488 | 200 µg/ml | $364.00 | |||
ZNF703 Antibody (E-6) Alexa Fluor® 546 | sc-271896 AF546 | 200 µg/ml | $364.00 | |||
ZNF703 Antibody (E-6) Alexa Fluor® 594 | sc-271896 AF594 | 200 µg/ml | $364.00 | |||
ZNF703 Antibody (E-6) Alexa Fluor® 647 | sc-271896 AF647 | 200 µg/ml | $364.00 | |||
ZNF703 Antibody (E-6) Alexa Fluor® 680 | sc-271896 AF680 | 200 µg/ml | $364.00 | |||
ZNF703 Antibody (E-6) Alexa Fluor® 790 | sc-271896 AF790 | 200 µg/ml | $364.00 | |||
ZNF703 (E-6) Neutralizing Peptide | sc-271896 P | 100 µg/0.5 ml | $69.00 |