ZNF313 Antibody (E-12): sc-514603

ZNF313 Antibody (E-12) is a mouse monoclonal IgG3 kappa light chain antibody that detects ZNF313 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-ZNF313 antibody (E-12) is available as the non-conjugated form. ZNF313, also known as RNF114 or ZNF228, is a 228 amino acid protein characterized by the presence of a RING-type zinc finger domain, which is crucial for its role in the ubiquitination pathway. ZNF313 is predominantly expressed in mature testis and exists in two isoforms due to alternative splicing, suggesting significant involvement in spermatogenesis and male fertility. ZNF313 function is essential, contributing to reproductive health and implicated in the pathogenesis of psoriasis, an immune-mediated skin condition that manifests as red, scaly patches on the skin. anti-ZNF313 antibody (E-12) enables exploration of ZNF313′s multifaceted roles in both reproductive biology and immune responses, providing valuable insights into potential therapeutic targeting.

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ZNF313 Antibody (E-12) References:

1. Identification of a novel human zinc finger protein gene ZNF313.  |  Ma, YX., et al. 2003. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 35: 230-7. PMID: 12621547
2. The KOX zinc finger genes: genome wide mapping of 368 ZNF PAC clones with zinc finger gene clusters predominantly in 23 chromosomal loci are confirmed by human sequences annotated in EnsEMBL.  |  Rousseau-Merck, MF., et al. 2002. Cytogenet Genome Res. 98: 147-53. PMID: 12697996
3. The KRAB domain of zinc finger gene ZNF268: a potential transcriptional repressor.  |  Sun, Y., et al. 2003. IUBMB Life. 55: 127-31. PMID: 12822888
4. Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome.  |  Englbrecht, CC., et al. 2004. BMC Genomics. 5: 39. PMID: 15236668
5. A novel subfamily of zinc finger genes involved in embryonic development.  |  Nakamura, M., et al. 2004. J Cell Biochem. 93: 887-95. PMID: 15449319
6. Cloning and expression analysis of a novel mouse zinc finger protein gene Znf313 abundantly expressed in testis.  |  Li, N., et al. 2007. J Biochem Mol Biol. 40: 270-6. PMID: 17394778
7. Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs.  |  O'Geen, H., et al. 2007. PLoS Genet. 3: e89. PMID: 17542650
8. Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene.  |  Capon, F., et al. 2008. Hum Mol Genet. 17: 1938-45. PMID: 18364390
9. Chromosomal localization of 9 KOX zinc finger genes: physical linkages suggest clustering of KOX genes on chromosomes 12, 16, and 19.  |  Rousseau-Merck, MF., et al. 1993. Hum Genet. 92: 583-7. PMID: 8262519

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ZNF313 Antibody (E-12) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ZNF313 Antibody (E-12) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ZNF313 Antibody (E-12) Specifications

Alternate Product Name: ZNF313

Product Clone Name: E-12

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids: 71-86

Epitope Target: ZNF313

Epitope Species: human

Product Reactivity/Detection: ZNF313

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ZNF313 Antibody (E-12): P: Blocking Peptide, X: TransCruz Reagent