ZNF313 Inhibitors refers to a class of chemical compounds specifically designed to target and modulate the activity of the zinc finger protein 313 (ZNF313). Zinc finger proteins are characterized by the presence of zinc-binding motifs that enable them to interact with various cellular components, influencing critical cellular processes such as transcriptional regulation and DNA repair. ZNF313, a member of this protein family, is involved in transcriptional regulation, exerting its effects by binding to specific DNA sequences. Inhibitors of ZNF313 are crafted to interfere with its normal functioning, thereby offering a means to investigate the intricate regulatory networks in which ZNF313 participates.
ZNF313 inhibitors typically involves a meticulous design process aimed at achieving selective and potent interactions with the target protein. Researchers employ structural biology, computational modeling, and medicinal chemistry approaches to identify small molecules that can bind to ZNF313 and modulate its activity. The chemical entities within this class often possess distinct structural features that enable them to engage with the target protein, disrupting its interactions with DNA or other cellular partners. Understanding the structural nuances of ZNF313 inhibitors is crucial for elucidating their mechanism of action and optimizing their potency and selectivity. As the field of chemical biology continues to advance, the exploration of ZNF313 inhibitors provides a valuable tool for researchers seeking to unravel the intricacies of gene regulation and cellular processes influenced by zinc finger proteins.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Incorporates into DNA and RNA, inhibits DNA methyltransferases, altering gene expression. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Inhibits histone deacetylases, leading to changes in chromatin structure and gene expression. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Binds to copper, potentially altering the structure and function of copper-dependent zinc fingers. | ||||||
1,10-Phenanthroline | 66-71-7 | sc-255888 sc-255888A | 2.5 g 5 g | $23.00 $32.00 | ||
Chelates metal ions, can strip zinc from zinc finger motifs, disrupting their structure. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Intercalates into DNA, altering DNA replication and transcription. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Inhibits DNA topoisomerase II, affecting DNA transcription and cell cycle. | ||||||
Ellipticine | 519-23-3 | sc-200878 sc-200878A | 10 mg 50 mg | $145.00 $569.00 | 4 | |
Intercalates in DNA and inhibits topoisomerase II, affecting DNA replication and transcription. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $321.00 | ||
Inhibits cyclin-dependent kinases, affecting cell cycle and potentially transcription. | ||||||
Quinomycin A | 512-64-1 | sc-202306 | 1 mg | $166.00 | 4 | |
Binds to DNA at the minor groove and inhibits transcription factors. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Inhibits transcriptional activity by affecting RNA polymerase II activity. | ||||||