ZNF24 Antibody (H-11): sc-393359
- ZNF24 Antibody (H-11) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 121-138 within an internal region of ZNF24 of human origin
- Anti-ZNF24 Antibody (H-11) is recommended for detection of ZNF24 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ZNF24 Antibody (H-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ZNF24 Antibody (H-11) for WB applications. These reagents are now offered in bundles with ZNF24 Antibody (H-11) (see ordering information below).
ZNF24 Antibody (H-11) is a mouse monoclonal IgG2b kappa light chain antibody that detects ZNF24 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-ZNF24 antibody (H-11) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZNF24, also known as zinc finger protein 24, ZNF191, KOX17, or ZSCAN3, is a 368 amino acid nuclear protein that plays a crucial role in transcriptional regulation. ZNF24 belongs to the Krüppel C2H2-type zinc-finger protein family and is characterized by four C2H2-type zinc fingers and one SCAN box domain. ZNF24 is predominantly expressed in various tissues, excluding the heart, and functions primarily as a transcriptional repressor, influencing the expression of key proteins such as vascular endothelial growth factor (VEGF), which is vital for angiogenesis and embryonic development. ZNF24′s ability to interact with KAP1 and recruit histone-modifying proteins underscores its importance in regulating gene expression and maintaining cellular homeostasis. ZNF24 can undergo phosphorylation by ATM or ATR in response to DNA damage, highlighting its potential role in cellular stress responses and the maintenance of genomic integrity.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZNF24 Antibody (H-11) References:
- The zinc finger-associated SCAN box is a conserved oligomerization domain. | Williams, AJ., et al. 1999. Mol Cell Biol. 19: 8526-35. PMID: 10567577
- Molecular cloning of six novel Krüppel-like zinc finger genes from hematopoietic cells and identification of a novel transregulatory domain KRNB. | Han, ZG., et al. 1999. J Biol Chem. 274: 35741-8. PMID: 10585455
- [Assignment of a novel zinc finger gene ZNF191 to human chromosome 18Q12.1 by human/rodent somatic cell hybrid panel and fluorescent in situ hybridization]. | Shi, SL., et al. 1998. Shi Yan Sheng Wu Xue Bao. 31: 21-7. PMID: 12014109
- Establishment of transgenic mice carrying gene encoding human zinc finger protein 191. | Li, JZ., et al. 2004. World J Gastroenterol. 10: 264-7. PMID: 14716836
- The zinc finger transcription factor 191 is required for early embryonic development and cell proliferation. | Li, J., et al. 2006. Exp Cell Res. 312: 3990-8. PMID: 17064688
- Overexpression and purification of single zinc finger peptides of human zinc finger protein ZNF191. | Zhao, DX., et al. 2007. Protein Expr Purif. 53: 232-7. PMID: 17270462
- Repression of vascular endothelial growth factor expression by the zinc finger transcription factor ZNF24. | Harper, J., et al. 2007. Cancer Res. 67: 8736-41. PMID: 17875714
- Chromosomal localization of two human zinc finger protein genes, ZNF24 (KOX17) and ZNF29 (KOX26), to 18q12 and 17p13-p12, respectively. | Rousseau-Merck, MF., et al. 1991. Genomics. 9: 154-61. PMID: 2004757
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF24 Antibody (H-11) | sc-393359 | 200 µg/ml | $316.00 | |||
ZNF24 Antibody (H-11): m-IgGκ BP-HRP Bundle | sc-523917 | 200 µg Ab, 40 µg BP | $354.00 | |||
ZNF24 Antibody (H-11): m-IgG2b BP-HRP Bundle | sc-549144 | 200 µg Ab; 10 µg BP | $354.00 | |||
ZNF24 Antibody (H-11) AC | sc-393359 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ZNF24 Antibody (H-11) HRP | sc-393359 HRP | 200 µg/ml | $316.00 | |||
ZNF24 Antibody (H-11) FITC | sc-393359 FITC | 200 µg/ml | $330.00 | |||
ZNF24 Antibody (H-11) PE | sc-393359 PE | 200 µg/ml | $343.00 | |||
ZNF24 Antibody (H-11) Alexa Fluor® 488 | sc-393359 AF488 | 200 µg/ml | $357.00 | |||
ZNF24 Antibody (H-11) Alexa Fluor® 546 | sc-393359 AF546 | 200 µg/ml | $357.00 | |||
ZNF24 Antibody (H-11) Alexa Fluor® 594 | sc-393359 AF594 | 200 µg/ml | $357.00 | |||
ZNF24 Antibody (H-11) Alexa Fluor® 647 | sc-393359 AF647 | 200 µg/ml | $357.00 | |||
ZNF24 Antibody (H-11) Alexa Fluor® 680 | sc-393359 AF680 | 200 µg/ml | $357.00 | |||
ZNF24 Antibody (H-11) Alexa Fluor® 790 | sc-393359 AF790 | 200 µg/ml | $357.00 | |||
ZNF24 (H-11) Neutralizing Peptide | sc-393359 P | 100 µg/0.5 ml | $68.00 |