ZNF193 Antibody (F-8): sc-398689

ZNF193 Antibody (F-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZNF193 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZNF193 Antibody (F-8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZNF193, also known as cell proliferation-inducing gene 12 protein, PRD51, or ZSCAN9, is a 394 amino acid nuclear protein that plays a crucial role in transcriptional regulation. As a member of the Krüppel C2H2-type zinc-finger protein family, ZNF193 features one SCAN box domain and five C2H2-type zinc fingers, which are essential for DNA binding and gene expression modulation. The presence of these zinc-finger motifs allows ZNF193 to interact with specific DNA sequences, thereby influencing the transcription of target genes involved in cell proliferation and differentiation. The gene encoding ZNF193 is located on human chromosome 6p22.1, and its proper function is vital for maintaining normal cellular processes, making ZNF193 an important target for research in cancer and developmental biology.

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ZNF193 Antibody (F-8) References:

1. The zinc finger-associated SCAN box is a conserved oligomerization domain.  |  Williams, AJ., et al. 1999. Mol Cell Biol. 19: 8526-35. PMID: 10567577
2. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.  |  Lichter, P., et al. 1992. Genomics. 13: 999-1007. PMID: 1505991
3. A family of human zinc finger proteins that bind methylated DNA and repress transcription.  |  Filion, GJ., et al. 2006. Mol Cell Biol. 26: 169-81. PMID: 16354688
4. A comprehensive catalog of human KRAB-associated zinc finger genes: insights into the evolutionary history of a large family of transcriptional repressors.  |  Huntley, S., et al. 2006. Genome Res. 16: 669-77. PMID: 16606702
5. [Progress in the study of KRAB zinc finger protein].  |  Tian, CY., et al. 2006. Yi Chuan. 28: 1451-6. PMID: 17098717
6. Characterization and mapping of human genes encoding zinc finger proteins.  |  Bray, P., et al. 1991. Proc Natl Acad Sci U S A. 88: 9563-7. PMID: 1946370
7. Upregulated expression of hITF in Crohn's disease and screening of hITF Interactant by a yeast two-hybrid system.  |  Shi, H., et al. 2010. Dig Dis Sci. 55: 2929-39. PMID: 20499178
8. Confirming TDP2 mutation in spinocerebellar ataxia autosomal recessive 23 (SCAR23).  |  Zagnoli-Vieira, G., et al. 2018. Neurol Genet. 4: e262. PMID: 30109272
9. The Effect of Genetic Variation on the Placental Transcriptome in Humans.  |  Kikas, T., et al. 2019. Front Genet. 10: 550. PMID: 31244887
10. Chromosome 6p SNP microhaplotypes and IgG3 levels in hemochromatosis probands with HFE p.C282Y homozygosity.  |  Barton, JC., et al. 2020. Blood Cells Mol Dis. 85: 102461. PMID: 32623342
11. Causal links between gut microbiomes, cytokines and risk of different subtypes of epilepsy: a Mendelian randomization study.  |  Qiu, Y., et al. 2024. Front Neurosci. 18: 1397430. PMID: 38855442
12. Three genes encoding zinc finger proteins on human chromosome 6p21.3: members of a new subclass of the Kruppel gene family containing the conserved SCAN box domain.  |  Lee, PL., et al. 1997. Genomics. 43: 191-201. PMID: 9244436

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ZNF193 Antibody (F-8) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-ZNF193 Antibody (F-8) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ZNF193 Antibody (F-8) Specifications

Alternate Product Name: ZNF193

Product Clone Name: F-8

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 191-256

Epitope Target: ZNF193

Epitope Species: human

Product Reactivity/Detection: ZNF193

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for ZNF193 Antibody (F-8): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin