ZKSCAN2 Antibody (F-8): sc-514383
- ZKSCAN2 Antibody (F-8) is a mouse monoclonal IgG1 κ ZKSCAN2 antibody provided at 200 µg/ml
- raised against amino acids 132-216 mapping within an internal region of ZKSCAN2 of human origin
- ZKSCAN2 Antibody (F-8) is recommended for detection of ZKSCAN2 of human origin by WB, IP, IF and ELISA
- Anti-ZKSCAN2 Antibody (F-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ZKSCAN2 Antibody (F-8) for WB applications. These reagents are now offered in bundles with ZKSCAN2 Antibody (F-8) (see ordering information below).
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ZKSCAN2 Antibody (F-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZKSCAN2 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZKSCAN2 (F-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZKSCAN2, also known as ZNF694, is a crucial member of the Krüppel C2H2-type zinc-finger protein family, characterized by six C2H2-type zinc fingers, one KRAB A domain, and one SCAN box domain, which play significant roles in transcriptional regulation. Located primarily in the nucleus, ZKSCAN2 functions as a transcriptional repressor, influencing gene expression and cellular processes. ZKSCAN2′s importance is underscored by involvement in various biological pathways, including those related to developmental processes and disease states. Notably, the gene encoding ZKSCAN2 is situated on human chromosome 16, a region associated with several genetic disorders, including Rubinstein-Taybi syndrome and Crohn′s disease, highlighting potential implications in health and disease. Alternative splicing of the ZKSCAN2 gene results in two distinct transcripts, further emphasizing the complexity and regulatory potential in cellular functions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZKSCAN2 Antibody (F-8) References:
- Complete sequencing and characterization of 21,243 full-length human cDNAs. | Ota, T., et al. 2004. Nat Genet. 36: 40-5. PMID: 14702039
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). | Gerhard, DS., et al. 2004. Genome Res. 14: 2121-7. PMID: 15489334
- The sequence and analysis of duplication-rich human chromosome 16. | Martin, J., et al. 2004. Nature. 432: 988-94. PMID: 15616553
- The full-ORF clone resource of the German cDNA Consortium. | Bechtel, S., et al. 2007. BMC Genomics. 8: 399. PMID: 17974005
- A quantitative atlas of mitotic phosphorylation. | Dephoure, N., et al. 2008. Proc Natl Acad Sci U S A. 105: 10762-7. PMID: 18669648
- The Rubinstein-Taybi syndrome: occurrence in two sets of identical twins. | Baraitser, M. and Preece, MA. 1983. Clin Genet. 23: 318-20. PMID: 6682729
- Rubinstein-Taybi syndrome caused by submicroscopic deletions within 16p13.3. | Breuning, MH., et al. 1993. Am J Hum Genet. 52: 249-54. PMID: 8430691
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZKSCAN2 Antibody (F-8) | sc-514383 | 200 µg/ml | $322.00 | |||
ZKSCAN2 Antibody (F-8): m-IgG Fc BP-HRP Bundle | sc-531105 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZKSCAN2 Antibody (F-8): m-IgGκ BP-HRP Bundle | sc-524703 | 200 µg Ab, 40 µg BP | $361.00 | |||
ZKSCAN2 Antibody (F-8): m-IgG1 BP-HRP Bundle | sc-544399 | 200 µg Ab; 20 µg BP | $361.00 | |||
ZKSCAN2 Antibody (F-8) AC | sc-514383 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ZKSCAN2 Antibody (F-8) HRP | sc-514383 HRP | 200 µg/ml | $322.00 | |||
ZKSCAN2 Antibody (F-8) FITC | sc-514383 FITC | 200 µg/ml | $336.00 | |||
ZKSCAN2 Antibody (F-8) PE | sc-514383 PE | 200 µg/ml | $349.00 | |||
ZKSCAN2 Antibody (F-8) Alexa Fluor® 488 | sc-514383 AF488 | 200 µg/ml | $364.00 | |||
ZKSCAN2 Antibody (F-8) Alexa Fluor® 546 | sc-514383 AF546 | 200 µg/ml | $364.00 | |||
ZKSCAN2 Antibody (F-8) Alexa Fluor® 594 | sc-514383 AF594 | 200 µg/ml | $364.00 | |||
ZKSCAN2 Antibody (F-8) Alexa Fluor® 647 | sc-514383 AF647 | 200 µg/ml | $364.00 | |||
ZKSCAN2 Antibody (F-8) Alexa Fluor® 680 | sc-514383 AF680 | 200 µg/ml | $364.00 | |||
ZKSCAN2 Antibody (F-8) Alexa Fluor® 790 | sc-514383 AF790 | 200 µg/ml | $364.00 |