ZHX2 Antibody (Z-07): sc-101256
- ZHX2 Antibody (Z-07) is a mouse monoclonal IgG2b κ, cited in 3 publications, provided at 100 µg/ml
- raised against recombinant ZHX2 of human origin
- recommended for detection of ZHX2 of human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ZHX2 Antibody (Z-07). This work is in progress.
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ZHX2 Antibody (Z-07) is a mouse monoclonal IgG2b antibody that detects ZHX2 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). ZHX2 is a crucial transcription factor that plays a significant role in regulating gene expression by acting as a transcriptional repressor, which is vital for maintaining cellular homeostasis and preventing aberrant gene activation that can lead to diseases such as cancer. ZHX2 is predominantly localized in the nucleus, where ZHX2 interacts with the activation domain of the A subunit of nuclear factor-Y (NF-YA), thereby influencing the transcriptional landscape of target genes. The presence of two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains in ZHX2 facilitates ZHX2′s ability to form homodimers and heterodimers, enhancing regulatory functions. Notably, hypermethylation-mediated silencing of ZHX2 has been implicated in hepatocellular carcinoma, highlighting ZHX2′s importance in cancer biology and potential as a biomarker or therapeutic target. Anti-ZHX2 antibody (Z-07) is an essential tool for researchers investigating the role of ZHX2 in various biological processes and disease states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZHX2 Antibody (Z-07) | sc-101256 | 100 µg/ml | $339.00 |