ZBED1 Antibody (H-2): sc-374061
- ZBED1 Antibody (H-2) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 627-651 near the C-terminus of ZBED1 of human origin
- recommended for detection of ZBED1 of human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine and bovine
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for ZBED1 Antibody (H-2) for WB applications. This reagent is now offered in a bundle with ZBED1 Antibody (H-2) (see ordering information below).
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ZBED1 Antibody (H-2) is a mouse monoclonal IgG2a antibody that detects ZBED1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZBED1, also known as zinc finger BED domain-containing protein 1, is a 694 amino acid protein that plays a crucial role in regulating ribosomal protein encoding genes, thereby influencing the cell cycle and cell proliferation. ZBED1 is predominantly localized to granular structures within the nucleus and is expressed at low levels across various tissues, with higher expression noted in the heart, placenta, spleen, and skeletal muscle. ZBED1 contains a BED-type zinc finger that specifically binds to the DNA sequence 5′-TGTCG[CT]GA[CT]A-3′, which is found in the promoters of ribosomal protein genes. This binding is essential for the transcriptional regulation of these genes, as ZBED1 also interacts with the promoter region of Histone H1, a protein vital for the condensation of nucleosomes into higher-order structures, thereby facilitating proper chromatin organization and gene expression. Anti-ZBED1 antibody (H-2) is an invaluable tool for researchers studying the intricate mechanisms of gene regulation and cellular proliferation in human tissues.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZBED1 Antibody (H-2) | sc-374061 | 200 µg/ml | $322.00 | |||
ZBED1 Antibody (H-2): m-IgG Fc BP-HRP Bundle | sc-540419 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZBED1 (H-2) Neutralizing Peptide | sc-374061 P | 100 µg/0.5 ml | $69.00 |