ZBED1 Antibody (H-9): sc-393684
- ZBED1 Antibody (H-9) is a mouse monoclonal IgG1 κ ZBED1 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of ZBED1 of human origin
- ZBED1 Antibody (H-9) is recommended for detection of ZBED1 of human origin by WB, IP, IF and ELISA
- Anti-ZBED1 Antibody (H-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ZBED1 Antibody (H-9) for WB applications. These reagents are now offered in bundles with ZBED1 Antibody (H-9) (see ordering information below).
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ZBED1 Antibody (H-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZBED1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZBED1 (H-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZBED1, or zinc finger BED domain-containing protein 1, is a 694 amino acid protein that plays a crucial role in cellular function by acting as a transcription factor. ZBED1 is primarily located in granular structures within the nucleus, where ZBED1 regulates the expression of ribosomal protein-encoding genes, thereby influencing the cell cycle and cell proliferation. ZBED1 contains a BED-type zinc finger that specifically binds to DNA regions within ribosomal protein promoters, particularly the sequence 5′-TGTCG[CT]GA[CT]A-3′. This binding is essential for the activation of transcription of ribosomal proteins, which are vital for ribosome biogenesis and protein synthesis. ZBED1 has been shown to interact with the promoter region of Histone H1, a protein necessary for the condensation of nucleosomes into higher-order structures, further underscoring ZBED1′s importance in maintaining genomic stability and regulating gene expression.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZBED1 Antibody (H-9) References:
- Identification of a human homologue of the DREF transcription factor with a potential role in regulation of the histone H1 gene. | Ohshima, N., et al. 2003. J Biol Chem. 278: 22928-38. PMID: 12663651
- Human DNA replication-related element binding factor (hDREF) self-association via hATC domain is necessary for its nuclear accumulation and DNA binding. | Yamashita, D., et al. 2007. J Biol Chem. 282: 7563-75. PMID: 17209048
- hDREF regulates cell proliferation and expression of ribosomal protein genes. | Yamashita, D., et al. 2007. Mol Cell Biol. 27: 2003-13. PMID: 17220279
- Mariner transposons in humans. | Oosumi, T., et al. 1995. Nature. 378: 672. PMID: 7501013
- Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. | Nagase, T., et al. 1998. DNA Res. 5: 277-86. PMID: 9872452
- A novel pseudoautosomal human gene encodes a putative protein similar to Ac-like transposases. | Esposito, T., et al. 1999. Hum Mol Genet. 8: 61-7. PMID: 9887332
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZBED1 Antibody (H-9) | sc-393684 | 200 µg/ml | $322.00 | |||
ZBED1 Antibody (H-9): m-IgG Fc BP-HRP Bundle | sc-527705 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZBED1 Antibody (H-9): m-IgG1 BP-HRP Bundle | sc-533078 | 200 µg Ab; 20 µg BP | $361.00 | |||
ZBED1 Antibody (H-9) AC | sc-393684 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ZBED1 Antibody (H-9) HRP | sc-393684 HRP | 200 µg/ml | $322.00 | |||
ZBED1 Antibody (H-9) FITC | sc-393684 FITC | 200 µg/ml | $336.00 | |||
ZBED1 Antibody (H-9) PE | sc-393684 PE | 200 µg/ml | $349.00 | |||
ZBED1 Antibody (H-9) Alexa Fluor® 488 | sc-393684 AF488 | 200 µg/ml | $364.00 | |||
ZBED1 Antibody (H-9) Alexa Fluor® 546 | sc-393684 AF546 | 200 µg/ml | $364.00 | |||
ZBED1 Antibody (H-9) Alexa Fluor® 594 | sc-393684 AF594 | 200 µg/ml | $364.00 | |||
ZBED1 Antibody (H-9) Alexa Fluor® 647 | sc-393684 AF647 | 200 µg/ml | $364.00 | |||
ZBED1 Antibody (H-9) Alexa Fluor® 680 | sc-393684 AF680 | 200 µg/ml | $364.00 | |||
ZBED1 Antibody (H-9) Alexa Fluor® 790 | sc-393684 AF790 | 200 µg/ml | $364.00 |