YY2 Antibody (A-5): sc-377008

YY2 Antibody (A-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects YY2 protein of mouse origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-YY2 antibody (A-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. YY2, a homologue of the YY1 transcription factor, plays a crucial role in gene regulation, exhibiting both transcriptional repression and activation functions. While YY2′s precise functions remain to be fully elucidated, YY2 interacts with specific promoters that are also regulated by YY1, suggesting a potential role in modulating gene expression in various biological contexts. YY2′s importance lies in the ability to influence the transcriptional landscape, which can have significant implications for cellular processes such as differentiation, proliferation, and response to environmental stimuli. Understanding YY2 dynamics and interactions with other proteins can provide valuable insights into the regulatory mechanisms governing gene expression and their impact on cellular function.

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YY2 Antibody (A-5) References:

1. Molecular cloning and functional characterization of the transcription factor YY2.  |  Nguyen, N., et al. 2004. J Biol Chem. 279: 25927-34. PMID: 15087442
2. Enhanceosome formation over the beta interferon promoter underlies a remote-control mechanism mediated by YY1 and YY2.  |  Klar, M. and Bode, J. 2005. Mol Cell Biol. 25: 10159-70. PMID: 16260628
3. Rapid evolution of a recently retroposed transcription factor YY2 in mammalian genomes.  |  Luo, C., et al. 2006. Genomics. 87: 348-55. PMID: 16377127
4. Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein.  |  Shi, Y., et al. 1991. Cell. 67: 377-88. PMID: 1655281
5. Delta, a transcription factor that binds to downstream elements in several polymerase II promoters, is a functionally versatile zinc finger protein.  |  Hariharan, N., et al. 1991. Proc Natl Acad Sci U S A. 88: 9799-803. PMID: 1946404
6. Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site.  |  Park, K. and Atchison, ML. 1991. Proc Natl Acad Sci U S A. 88: 9804-8. PMID: 1946405

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-YY2 Antibody (A-5) has 4 citations in a variety of scientific publications.

Primary antibodies like Anti-YY2 Antibody (A-5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

YY2 Antibody (A-5) Specifications

Alternate Product Name: YY2

Product Clone Name: A-5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 100-178

Epitope Target: YY2

Epitope Species: mouse

Product Reactivity/Detection: YY2

Species Reactivity/Detection: mouse

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 4 citations in various scientific publications

Available Conjugates/Forms for YY2 Antibody (A-5): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred YY2 antibody is YY2 Antibody (C-10): sc-374455.