WDR49 Antibody (E-9): sc-390195
- WDR49 Antibody (E-9) is a mouse monoclonal IgG1 κ WDR49 antibody provided at 200 µg/ml
- raised against a peptide mapping within an internal region of WDR49 of human origin
- WDR49 Antibody (E-9) is recommended for detection of WDR49 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including porcine
- Anti-WDR49 Antibody (E-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for WDR49 Antibody (E-9) for WB applications. These reagents are now offered in bundles with WDR49 Antibody (E-9) (see ordering information below).
WDR49 Antibody (E-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects WDR49 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). WDR49 Antibody (E-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. WDR49, also known as WD repeat-containing protein 49, consists of 697 amino acids and features eight WD repeats, which are structural motifs that facilitate protein-protein interactions. These WD repeats are crucial for WDR49′s role in assembling multi-protein complexes that regulate various cellular processes, including signal transduction and transcriptional regulation. The presence of these repeats allows WDR49 to participate in essential regulatory mechanisms, influencing cell cycle control and apoptosis. The gene encoding WDR49 is located on human chromosome 3, a region that encompasses approximately 214 million bases and contains over 1,100 genes, including those associated with cancer. Understanding WDR49′s function and interactions is vital for elucidating its role in cellular homeostasis and disease mechanisms, making anti-WDR49 antibody (E-9) an invaluable tool for researchers studying these pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
WDR49 Antibody (E-9) References:
- The WD repeat: a common architecture for diverse functions. | Smith, TF., et al. 1999. Trends Biochem Sci. 24: 181-5. PMID: 10322433
- Thirty-plus functional families from a single motif. | Yu, L., et al. 2000. Protein Sci. 9: 2470-6. PMID: 11206068
- WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases. | Li, D. and Roberts, R. 2001. Cell Mol Life Sci. 58: 2085-97. PMID: 11814058
- The WD-repeat protein superfamily in Arabidopsis: conservation and divergence in structure and function. | van Nocker, S. and Ludwig, P. 2003. BMC Genomics. 4: 50. PMID: 14672542
- The consensus coding sequences of human breast and colorectal cancers. | Sjöblom, T., et al. 2006. Science. 314: 268-74. PMID: 16959974
- A quantitative atlas of mitotic phosphorylation. | Dephoure, N., et al. 2008. Proc Natl Acad Sci U S A. 105: 10762-7. PMID: 18669648
- Phylogenetic, structural and functional relationships between WD- and Kelch-repeat proteins. | Hudson, AM. and Cooley, L. 2008. Subcell Biochem. 48: 6-19. PMID: 18925367
- The ancient regulatory-protein family of WD-repeat proteins. | Neer, EJ., et al. 1994. Nature. 371: 297-300. PMID: 8090199
- Folding of proteins with WD-repeats: comparison of six members of the WD-repeat superfamily to the G protein beta subunit. | Garcia-Higuera, I., et al. 1996. Biochemistry. 35: 13985-94. PMID: 8909296
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WDR49 Antibody (E-9) | sc-390195 | 200 µg/ml | $322.00 | |||
WDR49 Antibody (E-9): m-IgG Fc BP-HRP Bundle | sc-530090 | 200 µg Ab; 10 µg BP | $361.00 | |||
WDR49 Antibody (E-9): m-IgGκ BP-HRP Bundle | sc-523444 | 200 µg Ab, 40 µg BP | $361.00 | |||
WDR49 Antibody (E-9): m-IgG1 BP-HRP Bundle | sc-543864 | 200 µg Ab; 20 µg BP | $361.00 | |||
WDR49 Antibody (E-9) AC | sc-390195 AC | 500 µg/ml, 25% agarose | $424.00 | |||
WDR49 Antibody (E-9) HRP | sc-390195 HRP | 200 µg/ml | $322.00 | |||
WDR49 Antibody (E-9) FITC | sc-390195 FITC | 200 µg/ml | $336.00 | |||
WDR49 Antibody (E-9) PE | sc-390195 PE | 200 µg/ml | $349.00 | |||
WDR49 Antibody (E-9) Alexa Fluor® 488 | sc-390195 AF488 | 200 µg/ml | $364.00 | |||
WDR49 Antibody (E-9) Alexa Fluor® 546 | sc-390195 AF546 | 200 µg/ml | $364.00 | |||
WDR49 Antibody (E-9) Alexa Fluor® 594 | sc-390195 AF594 | 200 µg/ml | $364.00 | |||
WDR49 Antibody (E-9) Alexa Fluor® 647 | sc-390195 AF647 | 200 µg/ml | $364.00 | |||
WDR49 Antibody (E-9) Alexa Fluor® 680 | sc-390195 AF680 | 200 µg/ml | $364.00 | |||
WDR49 Antibody (E-9) Alexa Fluor® 790 | sc-390195 AF790 | 200 µg/ml | $364.00 | |||
WDR49 (E-9) Neutralizing Peptide | sc-390195 P | 100 µg/0.5 ml | $69.00 |