VPS37A Antibody (G-3): sc-376978
- VPS37A Antibody (G-3) is a mouse monoclonal IgG1 κ VPS37A antibody, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 81-380 mapping within an internal region of VPS37A of human origin
- VPS37A Antibody (G-3) is recommended for detection of VPS37A of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-VPS37A Antibody (G-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for VPS37A Antibody (G-3) for WB and IHC(P) applications. These reagents are now offered in bundles with VPS37A Antibody (G-3) (see ordering information below).
VPS37A Antibody (G-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects VPS37A of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). VPS37A monoclonal antibody (G-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. VPS37A, also known as vacuolar protein sorting 37 homolog A or HCRP1, is a 397 amino acid protein that plays a crucial role in the endosomal sorting complex required for transport I (ESCRT-I) complex, which is essential for proper protein trafficking to the vacuole. VPS37A is primarily localized to the nucleus, peripheral membranes, and late endosome membranes, highlighting VPS37A′s importance in cellular processes. VPS37A is expressed in various tissues, with particularly high levels in the liver, and is involved in vesicular trafficking, protein sorting, cell growth, and differentiation. Notably, VPS37A undergoes alternative splicing, resulting in multiple isoforms that may have distinct functions or regulatory mechanisms, further emphasizing VPS37A′s complexity and significance in cellular dynamics.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
VPS37A Antibody (G-3) References:
- Membrane transport: ubiquitylation in endosomal sorting. | Dupré, S., et al. 2001. Curr Biol. 11: R932-4. PMID: 11719242
- HCRP1, a novel gene that is downregulated in hepatocellular carcinoma, encodes a growth-inhibitory protein. | Xu, Z., et al. 2003. Biochem Biophys Res Commun. 311: 1057-66. PMID: 14623289
- The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding. | Stuchell, MD., et al. 2004. J Biol Chem. 279: 36059-71. PMID: 15218037
- The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation. | Bache, KG., et al. 2004. Mol Biol Cell. 15: 4337-46. PMID: 15240819
- Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding. | Eastman, SW., et al. 2005. J Biol Chem. 280: 628-36. PMID: 15509564
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VPS37A Antibody (G-3) | sc-376978 | 200 µg/ml | $322.00 | |||
VPS37A Antibody (G-3): m-IgG Fc BP-HRP Bundle | sc-527566 | 200 µg Ab; 10 µg BP | $361.00 | |||
VPS37A Antibody (G-3): m-IgG1 BP-HRP Bundle | sc-532939 | 200 µg Ab; 20 µg BP | $361.00 | |||
VPS37A Antibody (G-3) AC | sc-376978 AC | 500 µg/ml, 25% agarose | $424.00 | |||
VPS37A Antibody (G-3) HRP | sc-376978 HRP | 200 µg/ml | $322.00 | |||
VPS37A Antibody (G-3) FITC | sc-376978 FITC | 200 µg/ml | $336.00 | |||
VPS37A Antibody (G-3) PE | sc-376978 PE | 200 µg/ml | $349.00 | |||
VPS37A Antibody (G-3) Alexa Fluor® 488 | sc-376978 AF488 | 200 µg/ml | $364.00 | |||
VPS37A Antibody (G-3) Alexa Fluor® 546 | sc-376978 AF546 | 200 µg/ml | $364.00 | |||
VPS37A Antibody (G-3) Alexa Fluor® 594 | sc-376978 AF594 | 200 µg/ml | $364.00 | |||
VPS37A Antibody (G-3) Alexa Fluor® 647 | sc-376978 AF647 | 200 µg/ml | $364.00 | |||
VPS37A Antibody (G-3) Alexa Fluor® 680 | sc-376978 AF680 | 200 µg/ml | $364.00 | |||
VPS37A Antibody (G-3) Alexa Fluor® 790 | sc-376978 AF790 | 200 µg/ml | $364.00 |