Date published: 2025-11-2

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VPS35 Antibodies

Santa Cruz Biotechnology offers a broad range of VPS35 monoclonal antibodies for investigating VPS35's role in cellular processes. VPS35 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). VPS35, a key component of the retromer complex, plays a crucial role in the recycling of membrane proteins and the maintenance of cellular homeostasis. The function of VPS35 is vital for proper protein trafficking, which is essential for various cellular processes, including signal transduction and endosomal sorting. Research has shown that VPS35 dysfunction is linked to several neurodegenerative diseases, highlighting its significance in neurological research. Understanding VPS35's molecular mechanisms can provide valuable insights into potential therapeutic strategies for treating neurodegenerative disorders. Investigating VPS35's interactions with other proteins can reveal new pathways involved in cellular trafficking and protein recycling. Current research focuses on understanding how VPS35 mutations affect cellular function and contribute to disease progression. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of VPS35's role in health and disease.

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VPS35 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

VPS35 Antibody (B-5)

sc-374372mouse IgG2b κ497-796 (h)WB, IP, IF, IHC(P), ELISAm, r, h
41
(18)

VPS35 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

VPS35 CRISPR/Cas9 KO Plasmid (h)

sc-402019hGene KnockoutGFP
1
(2)

VPS35 HDR Plasmid (h)

sc-402019-HDRhHomology Directed RepairPuromycin
1
(2)

VPS35 Double Nickase Plasmid (h)

sc-402019-NIChGene KnockoutPuromycin
1
(2)

VPS35 Double Nickase Plasmid (h2)

sc-402019-NIC-2hGene KnockoutPuromycin
1
(2)

VPS35 CRISPR/Cas9 KO Plasmid (m)

sc-425759mGene KnockoutGFP0
(0)

VPS35 HDR Plasmid (m)

sc-425759-HDRmHomology Directed RepairPuromycin0
(0)

VPS35 Double Nickase Plasmid (m)

sc-425759-NICmGene KnockoutPuromycin0
(0)

VPS35 Double Nickase Plasmid (m2)

sc-425759-NIC-2mGene KnockoutPuromycin0
(0)

VPS35 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

VPS35 CRISPR Activation Plasmid (h)

sc-402019-ACThGene ActivationPuro, Blast, Hygro
1
(2)

VPS35 CRISPR Activation Plasmid (h2)

sc-402019-ACT-2hGene ActivationPuro, Blast, Hygro
1
(2)

VPS35 Lentiviral Activation Particles (h)

sc-402019-LAChGene ActivationPuro, Blast, Hygro
1
(2)

VPS35 Lentiviral Activation Particles (h2)

sc-402019-LAC-2hGene ActivationPuro, Blast, Hygro
1
(2)

VPS35 CRISPR Activation Plasmid (m)

sc-425759-ACTmGene ActivationPuro, Blast, Hygro0
(0)

VPS35 CRISPR Activation Plasmid (m2)

sc-425759-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

VPS35 Lentiviral Activation Particles (m)

sc-425759-LACmGene ActivationPuro, Blast, Hygro0
(0)

VPS35 Lentiviral Activation Particles (m2)

sc-425759-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

VPS35 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

VPS35 siRNA (h)

sc-63218hGene SilencingN/A0
(0)

VPS35 shRNA Plasmid (h)

sc-63218-SHhGene SilencingPuromycin0
(0)

VPS35 shRNA (h) Lentiviral Particles

sc-63218-VhGene SilencingPuromycin0
(0)

VPS35 siRNA (m)

sc-63219mGene SilencingN/A
3
(0)

VPS35 shRNA Plasmid (m)

sc-63219-SHmGene SilencingPuromycin
3
(0)

VPS35 shRNA (m) Lentiviral Particles

sc-63219-VmGene SilencingPuromycin
3
(0)