
Vinculin Antibody (V284) is a mouse monoclonal IgG1 antibody that detects vinculin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-vinculin antibody (V284) plays a crucial role in cellular adhesion and signaling by linking the actin cytoskeleton to integrins at focal adhesions, which are essential for maintaining cell shape and facilitating communication with the extracellular matrix. Vinculin is primarily located at the plasma membrane, where vinculin forms complexes with other cytoskeletal proteins, such as talin and α-actinin, to stabilize cell adhesion and promote cellular responses to mechanical stress. Proper functioning of vinculin is vital for processes like cell migration, tissue repair, and the overall integrity of tissues, making vinculin a significant focus of study in various fields, including cancer research and developmental biology. Anti-vinculin antibody (V284) serves as an invaluable tool for researchers aiming to explore the dynamics of cell adhesion and the intricate signaling pathways that govern cellular behavior.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
vinculin Antibody (V284) | sc-59803 | 200 µg/ml | $322.00 | |||
vinculin Antibody (V284): m-IgG Fc BP-HRP Bundle | sc-539140 | 200 µg Ab; 10 µg BP | $361.00 | |||
vinculin Antibody (V284): m-IgG1 BP-HRP Bundle | sc-541288 | 200 µg Ab; 20 µg BP | $361.00 |