vinculin Antibody (2Q1087): sc-73264
- vinculin Antibody (2Q1087) is a mouse monoclonal IgG1 κ, cited in 4 publications, provided at 200 µg/ml
- raised against vinculin from platelets of human origin
- recommended for detection of vinculin of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See vinculin (7F9): sc-73614 for vinculin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for vinculin Antibody (2Q1087) for WB and IHC(P) applications. These reagents are now offered in bundles with vinculin Antibody (2Q1087) (see ordering information below).
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SEE ALSO...
Vinculin Antibody (2Q1087) is a mouse monoclonal IgG1 antibody that detects vinculin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Vinculin plays a crucial role in cellular adhesion and mechanotransduction, serving as a key component of focal adhesions that connect the actin cytoskeleton to the extracellular matrix. This connection is vital for maintaining cell shape, facilitating cell migration, and transmitting mechanical signals from the environment to the cell interior, which can influence various cellular processes, including proliferation and differentiation. The structure of vinculin contains multiple domains that allow interaction with other cytoskeletal proteins, such as talin and α-actinin, thereby forming a complex that stabilizes adhesion sites. Vinculin′s ability to undergo conformational changes in response to mechanical stress enhances functionality in dynamic cellular environments. Anti-vinculin antibody (2Q1087) enables researchers to gain insights into cell adhesion mechanisms and vinculin′s role in various physiological and pathological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
vinculin Antibody (2Q1087) | sc-73264 | 200 µg/ml | $322.00 | |||
vinculin Antibody (2Q1087): m-IgG Fc BP-HRP Bundle | sc-539466 | 200 µg Ab; 10 µg BP | $361.00 | |||
vinculin Antibody (2Q1087): m-IgG1 BP-HRP Bundle | sc-541506 | 200 µg Ab; 20 µg BP | $361.00 |