
VHR Antibody (24) is a mouse monoclonal IgG1 antibody that recognizes VHR in mouse, rat, human, and canine samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). VHR, also known as dual specificity phosphatase 1 (DUSP1), plays a crucial role in regulating cellular signaling pathways by dephosphorylating both phosphothreonine and phosphotyrosine residues on mitogen-activated protein kinases (MAPKs). This regulation is vital for maintaining cellular homeostasis and responding to various extracellular signals, including growth factors and stressors. By modulating the activity of MAPKs such as MAPK/ERK, SAPK/JNK, and p38, VHR influences numerous physiological processes, including cell proliferation, differentiation, and apoptosis. VHR expression is particularly important in tissues such as breast and ovarian tissues, where VHR may contribute to the development and progression of certain cancers. Anti-VHR antibody (24) serves as an essential tool for researchers investigating the intricate signaling networks that govern cellular responses and the potential implications of dysregulation in disease states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VHR Antibody (24) | sc-136118 | 50 µg/0.5 ml | $322.00 |