
VEZF1 Antibody (C-10) is a mouse monoclonal IgG1 antibody that detects VEZF1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). VEZF1, also known as ZNF161 or DB1, is a crucial nuclear-localizing zinc-finger protein that plays a significant role in the regulation of endothelial gene expression, particularly in cardiovascular development. VEZF1 is predominantly expressed in the kidneys and skeletal muscle, where VEZF1 functions as a transcription factor that modulates the expression of endothelin-1 (ET-1) by binding to the CT/GC-rich region of the ET-1 promoter. VEZF1′s ability to activate ET-1 expression is vital for proper assembly of the cardiovascular system during early embryonic development, as VEZF1 influences the formation and function of the vascular endothelium. Additionally, VEZF1 is characterized by its Krüppel-type DNA-binding domain and KRAB domain, which are essential for interaction with KAP1 and recruitment of histone-modifying proteins, thereby facilitating transcriptional regulation. Anti-VEZF1 antibody (C-10) is an invaluable tool for researchers studying vascular biology and molecular mechanisms underlying cardiovascular development and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VEZF1 Antibody (C-10) | sc-365561 | 200 µg/ml | $322.00 | |||
VEZF1 Antibody (C-10): m-IgG Fc BP-HRP Bundle | sc-537815 | 200 µg Ab; 10 µg BP | $361.00 | |||
VEZF1 Antibody (C-10): m-IgGκ BP-HRP Bundle | sc-535222 | 200 µg Ab; 40 µg BP | $361.00 | |||
VEZF1 Antibody (C-10): m-IgG1 BP-HRP Bundle | sc-545373 | 200 µg Ab; 20 µg BP | $361.00 | |||
VEZF1 Antibody (C-10) X | sc-365561 X | 200 µg/0.1 ml | $322.00 |