vanin-1 Antibody (3-RE8): sc-135599
- vanin-1 Antibody (3-RE8) is a mouse monoclonal IgG2a κ vanin-1 antibody provided at 100 µg/ml
- raised against recombinant vanin-1 protein of human origin
- recommended for detection of vanin-1 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for vanin-1 Antibody (3-RE8). This work is in progress.
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vanin-1 Antibody (3-RE8) is a mouse monoclonal IgG2a kappa light chain antibody that detects vanin-1 of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). anti-vanin-1 antibody (3-RE8) is available as a non-conjugated format. vanin-1 plays a crucial role in cellular metabolism as a pantetheinase enzyme, which is responsible for the hydrolysis of pantetheine, thereby facilitating the recycling of vitamin B5. This function is particularly important because vitamin B5 is essential for the synthesis of coenzyme A, a vital cofactor in numerous biochemical reactions, including fatty acid metabolism and the citric acid cycle. Additionally, vanin-1 generates cysteamine, a potent antioxidant that protects cells from oxidative stress, highlighting its significance in maintaining cellular health. vanin-1 expression is widespread, with notable presence in the spleen, liver, and small intestine, where vanin-1 may contribute to vitamin B5 salvage pathways. In the developing testis of mice, vanin-1 is specifically expressed in male Sertoli cells, aiding in their migration, which is critical for proper testicular development. The gene encoding human vanin-1 is located on chromosome 6q23-q24, and vanin-1 is part of a family that includes vanin-2 and vanin-3, which may have overlapping or distinct biological functions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
vanin-1 Antibody (3-RE8) | sc-135599 | 100 µg/ml | $339.00 |