USP43 Antibody (H-10): sc-393895
- USP43 Antibody (H-10) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1094-1115 at the C-terminus of USP43 of human origin
- recommended for detection of USP43 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for USP43 Antibody (H-10) for WB applications. These reagents are now offered in bundles with USP43 Antibody (H-10) (see ordering information below).
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through various enzymes that add or remove ubiquitin, the Ub pathway regulates many intracellular processes including signal transduction, transcriptional activation and cell cycle progression. USP43 (ubiquitin specific peptidase 43), also known as deubiquitinating enzyme 43 or ubiquitin thioesterase 43, functions as a 1,124 amino acid protein belonging to the peptidase C19 family. USP43 hydrolyzes the peptide bond of C-terminal glycine of ubiquitin, playing an important role in processing ubiquinated proteins and poly-ubiquitin precursors. USP43 shows low expression in lung, aorta and brain, with encoding by a gene mapping to human chromosome 17p13.1. Alternative splicing events result in three USP43 isoforms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
USP43 Antibody (H-10) | sc-393895 | 200 µg/ml | $316.00 | |||
USP43 Antibody (H-10): m-IgGκ BP-HRP Bundle | sc-535922 | 200 µg Ab; 40 µg BP | $354.00 | |||
USP43 Antibody (H-10): m-IgG2b BP-HRP Bundle | sc-549489 | 200 µg Ab; 10 µg BP | $354.00 | |||
USP43 (H-10) Neutralizing Peptide | sc-393895 P | 100 µg/0.5 ml | $68.00 |